抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

Probability Distributions.- Linear Models for Regression.- Linear Models for Classification.- Neural Networks.- Kernel Methods.- Sparse Kernel Machines.- Graphical Models.- Mixture Models and EM.- Approximate Inference.- Sampling Methods.- Continuous Latent Variables.- Sequential Data.- Combining Models.

Pattern Recognition and Machine Learning

The 11th edition of Harrison's Principles of Internal Medicine welcomes Anthony Fauci to its editorial staff, in addition to more than 85 new contributors. While the organization of the book is similar to previous editions, major emphasis has been placed on disorders that affect multiple organ systems. Important advances in genetics, immunology, and oncology are emphasized. Many chapters of the book have been rewritten and describe major advances in internal medicine. Subjects that received only a paragraph or two of attention in previous editions are now covered in entire chapters. Among the chapters that have been extensively revised are the chapters on infections in the compromised host, on skin rashes in infections, on many of the viral infections, including cytomegalovirus and Epstein-Barr virus, on sexually transmitted diseases, on diabetes mellitus, on disorders of bone and mineral metabolism, and on lymphadenopathy and splenomegaly. The major revisions in these chapters and many

Harrison's Principles of Internal Medicine

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

Nanocrystals are fundamental to modern science and technology. Mastery over the shape of a nanocrystal enables control of its properties and enhancement of its usefulness for a given application. Our aim is to present a comprehensive review of current research activities that center on the shape-controlled synthesis of metal nanocrystals. We begin with a brief introduction to nucleation and growth within the context of metal nanocrystal synthesis, followed by a discussion of the possible shapes that a metal nanocrystal might take under different conditions. We then focus on a variety of experimental parameters that have been explored to manipulate the nucleation and growth of metal nanocrystals in solution-phase syntheses in an effort to generate specific shapes. We then elaborate on these approaches by selecting examples in which there is already reasonable understanding for the observed shape control or at least the protocols have proven to be reproducible and controllable. Finally, we highlight a number of applications that have been enabled and/or enhanced by the shape-controlled synthesis of metal nanocrystals. We conclude this article with personal perspectives on the directions toward which future research in this field might take.

Shape‐Controlled Synthesis of Metal Nanocrystals: Simple Chemistry Meets Complex Physics?

Thermal covert channel (TCC) attacks have been a serious security concern to the use of many-core chips. Severity of these attacks is directly linked to the TCC’s transmission rate and its BER (bit error rate) performance, both of which are impacted by the transmission characteristics of thermal signals and adopted encoding, modulation, and multiplexing schemes. This paper examines, compares, and analyzes various TCCs built upon different combinations of encoding, modulation, and multiplexing. In particular, our study shows that TCC using non-return-to-zero (NRZ) line coding and frequency shift keying (FSK) modulation achieves the highest throughput of 120 bps and BER of below 10%.

On Evaluation of On-chip Thermal Covert Channel Attacks

|A planar UHF RFID tag antenna with a hybrid nested slot and T-match network is presented. A novel T-match network in a nested slot is introduced to have superior conjugate impedance matching between tag antenna and the semiconductor microchip. Size curtailment is acquired by means of exploiting the T-match network branches and feeder strip line. Moreover, expanding the nested slot area and increasing the T-match branch length modify the electrical length and increase the antenna inductance. Thus by utilizing the arm of matching network and feeder, conjugate impedance is achieved in accordance with the semiconductor chip at 865 MHz. A surpassing UHF tag with volume 120 (cid:2) 60 (cid:2) 1 : 6 mm 3 (0 : 346 (cid:21) (cid:2) 0 : 173 (cid:21) (cid:2) 0 : 0046 (cid:21) ), with outstanding 10-dB return loss of 12 MHz, has been (cid:13)ourishingly demonstrated, and it is able to obtain a detection range of 13.9 m. This tag antenna composition is simulated with respect to 4 W EIRP reader.

A Nested Slot and T-match Network Based Hybrid Antenna for UHF RFID Tag Applications

Coal resources occurring in thick seams1 in India account for 70 percent of the total workable coal reserves. Evaluation of suitable techniques to extract thick seams has been the main concern of the mining engineers in this country, perhaps, since the coal mining began in India around 200 years ago and more seriously since 1930s. Thick coal seams with a higher concentration of coal reserve, economically a boon, have posed a serious problem of exploitation due to their low level of recovery, difficult strata control, problem of heating and fire, gradient and nature of strata and coal seam. The convenient working height by the conventional method was 3 to 3.5m due to restricted maneuverability in loosening of coal. The resistance of the conventional props/chocks also decreases with height due to high slenderness ratio. The problem is more acute in Raniganj and Jharia Coalfields, where a number of good quality coal seams were developed on pillars leaving a coal band mainly along the roof horizone. A cable bolting based semi-mechanised depillaring method has been developed at Central Mining Research Institute (CMRI) to tackle the problem of thick seam mining. This method was successfully experimented at NCPH mine of M/s South Eastern Coalfields Limited (SECL). Upper Kajora seam of 6.5 to 7.5m thickness developed on pillars in Madhusudanpur 7 pit & Incline colliery of M/s Eastern Coalfields Limited (ECL) was selected for further trial of this method. This paper presents the field trial of this method at Madhussudanpur colliery along with the results of strata behaviour study done in a panel under shallow depth of cover.

Depillaring of a thick coal seam using cable bolts under shallow depth cover - a case study

The information about the positions of the primary users (PUs) is imperative for the functioning of Cognitive Radio Networks (CRNs) as it may turn out to be advantageous for improving the utilization of spectrum and also for avoiding the detrimental intervention. Extant Range-based techniques fail to work in some scenarios i.e. If the condition required for the application of trilateration method is not fulfilled which means the circle drawn for the SUs have no common point of intersection between them. Through this work we are moving one step further in making the CRN work more efficiently by presenting a Centroid based licensed user localization technique to get the location of PU (i.e. the licensed user) using RSS. The proposed method counts on the information obtained from three SUs and the Centroid concept to accomplish the localization process.

Centroid-based primary user localization in Cognitive Radio Network using RSS

The purpose of this study was to compare selected motor fitness component levels among the Uttarakhand state level racket sports players. one hundred fifty (150) subjects, 50 badmintons, 50 table tennis and 50 squash players were selected from the Uttarakhand State for this study. The age of the selected subjects ranges from 16 to 19 years. Motors fitness tests were administered to find out the various motor fitness components (muscular power, strength and endurance) among the different racket sports. For statistical analysis and interpretation of data ‘F’ test (Anova) was conducted to test for significatant difference (0.05) among the groups. Result showed that Badminton players were comparatively better than table tennis and squash sports player in all the selected motor fitness components.

https://www.kheljournal.com/archives/2017/vol4issue3/PartD/4-3-57-883.pdf

Amit Singh

Papers

On Evaluation of On-chip Thermal Covert Channel Attacks

A Nested Slot and T-match Network Based Hybrid Antenna for UHF RFID Tag Applications

Depillaring of a thick coal seam using cable bolts under shallow depth cover - a case study

Centroid-based primary user localization in Cognitive Radio Network using RSS

A comparative study of selected motor fitness components among badminton table tennis and squash