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Amy K. Patick
Researcher at Santaris Pharma a/s
Publications - 3
Citations - 2157
Amy K. Patick is an academic researcher from Santaris Pharma a/s. The author has contributed to research in topics: MiR-122 & Hepatitis C virus. The author has an hindex of 3, co-authored 3 publications receiving 1925 citations.
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Journal ArticleDOI
Treatment of HCV Infection by Targeting MicroRNA
Harry L.A. Janssen,Hendrik W. Reesink,Eric Lawitz,Stefan Zeuzem,Maribel Rodriguez-Torres,Keyur Patel,Adriaan J. van der Meer,Amy K. Patick,Alice Chen,Yi Zhou,Robert Persson,Barney D King,Sakari Kauppinen,Arthur A. Levin,Michael R. Hodges +14 more
TL;DR: The use of miravirsen in patients with chronic HCV genotype 1 infection showed prolonged dose-dependent reductions in HCV RNA levels without evidence of viral resistance.
Journal ArticleDOI
In Vitro Antiviral Activity and Preclinical and Clinical Resistance Profile of Miravirsen, a Novel Anti-Hepatitis C Virus Therapeutic Targeting the Human Factor miR-122
Søren Ottosen,Todd B. Parsley,Lu Yang,K. Zeh,Leen-Jan van Doorn,Eva van der Veer,Anneke K. Raney,Michael R. Hodges,Amy K. Patick +8 more
TL;DR: Miravirsen is a β-doxy-locked nucleic acid-modified phosphorothioate antisense oligonucleotide targeting the liver-specific microRNA-122 (miR-122).