An-Na Chiang

TL;DR: It was found that apoB concentration progressively increased with advancing gestation, while the levels of apoA-I, Lp(a) and blood sugar were independent of gestation process, and the physiological significance of hyperlipidemia during pregnancy is discussed.

TL;DR: The findings suggest that inhibition of SR-A-mediated oxLDL uptake and promotion of ABCA1-dependent cholesterol efflux are two crucial events in suppression of cholesterol accumulation by curcumin in the transformation of macrophage foam cells.

TL;DR: The ex vivo study revealed that BRE had significantly stronger ability to inhibit LDL oxidation than white rice extract (WRE) and antioxidative effects exerted by BRE are mediated through decreases in free-radical generation as well as increases in SOD and CAT activities both in vitro and in vivo.

TL;DR: The data suggest that the neuroprotective mechanisms of DHA pretreatment are, in part, mediated by attenuating damaging mechanisms through reduction of cytotoxic factor production and by strengthening survival mechanisms through ERK-mediated and/or Bcl-2-mediated prosurvival cascade.

TL;DR: FO reduced the formation of atherosclerotic lesions in the aortic arteries of apoE(-/-) mice not through any lipid-lowering effect and may result from its antioxidative defense mechanism through the induction of antioxidant enzyme activities.