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Ana María Sánchez-Pérez
Researcher at James I University
Publications - 55
Citations - 1812
Ana María Sánchez-Pérez is an academic researcher from James I University. The author has contributed to research in topics: Receptor & NMDA receptor. The author has an hindex of 22, co-authored 49 publications receiving 1565 citations. Previous affiliations of Ana María Sánchez-Pérez include University of Valencia & University of California, San Francisco.
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Journal ArticleDOI
Supersensitivity to allosteric GABA A receptor modulators and alcohol in mice lacking PKCε
Clyde W. Hodge,Kristin K. Mehmert,Stephen P. Kelley,Thomas A. McMahon,Ashley Haywood,M. Foster Olive,Dan Wang,Ana María Sánchez-Pérez,Robert O. Messing +8 more
TL;DR: It is demonstrated that mutant mice lacking protein kinase C epsilon (PKCε) were more sensitive than wild-type littermates to the acute behavioral effects of ethanol and other drugs that allosterically activate GABAA receptors.
Journal ArticleDOI
Glutamine synthetase activity and glutamine content in brain: modulation by NMDA receptors and nitric oxide.
Elena Kosenko,Marta Llansola,Carmina Montoliu,Pilar Monfort,Regina Rodrigo,Mariluz Hernández-Viadel,Slaven Erceg,Ana María Sánchez-Pérez,Vicente Felipo +8 more
TL;DR: It is found that glutamine synthetase activity and glutamine content in brain are modulated by NMDA receptors and nitric oxide, and this may be useful, for example, to increase ammonia detoxification in brain in hyperammonemic situations.
Journal ArticleDOI
Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cε
Clyde W. Hodge,Jacob Raber,Thomas A. McMahon,Helen Walter,Ana María Sánchez-Pérez,M. Foster Olive,Kristin K. Mehmert,A. Leslie Morrow,Robert O. Messing +8 more
TL;DR: It is suggested that increased GABA(A) receptor sensitivity to neurosteroids contributes to reduced anxiety-like behavior and stress hormone responses in PKCepsilon-null mice and is a possible therapeutic target for development of anxiolytics.
Journal ArticleDOI
Cypin: a cytosolic regulator of PSD-95 postsynaptic targeting
Bonnie L. Firestein,Jay E. Brenman,Chiye Aoki,Ana María Sánchez-Pérez,Alaa El-Husseini,David S. Bredt +5 more
TL;DR: Overexpression of cypin in hippocampal neurons specifically perturbs postsynaptic trafficking of PSD-95 and SAP-102, an effect not produced by overeexpression of other PDZ ligands.
Journal ArticleDOI
Modulation of NMDA receptors in the cerebellum. 1. Properties of the NMDA receptor that modulate its function
TL;DR: This and the accompanying review summarize the information available on the modulation of NMDA receptors in cerebellum and reviews the properties of the NMDA receptor that modulate its function: subunit composition, post-translational modifications and synaptic localization.