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Anastasia Ragulskaya
Researcher at University of Tübingen
Publications - 11
Citations - 90
Anastasia Ragulskaya is an academic researcher from University of Tübingen. The author has contributed to research in topics: Medicine & Phase transition. The author has an hindex of 3, co-authored 6 publications receiving 25 citations.
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Journal ArticleDOI
Microscopic Dynamics of Liquid-Liquid Phase Separation and Domain Coarsening in a Protein Solution Revealed by X-Ray Photon Correlation Spectroscopy
Anita Girelli,Hendrik Rahmann,Nafisa Begam,Anastasia Ragulskaya,Mario Reiser,Sivasurender Chandran,Sivasurender Chandran,Fabian Westermeier,Michael Sprung,Fajun Zhang,Christian Gutt,Frank Schreiber +11 more
TL;DR: In this article, the authors used x-ray photon correlation spectroscopy to determine the liquid-liquid phase separation dynamics of a model protein solution upon low temperature quenches and find distinctly different dynamical regimes.
Journal ArticleDOI
Kinetics of Network Formation and Heterogeneous Dynamics of an Egg White Gel Revealed by Coherent X-Ray Scattering.
Nafisa Begam,Anastasia Ragulskaya,Anita Girelli,Hendrik Rahmann,Sivasurender Chandran,Fabian Westermeier,Mario Reiser,Michael Sprung,Fajun Zhang,Christian Gutt,Frank Schreiber +10 more
TL;DR: In this article, the kinetics of heat-induced gelation and the microscopic dynamics of a hen egg white gel are probed using x-ray photon correlation spectroscopy along with ultrasmall-angle xray scattering, revealing an exponential growth of the characteristic relaxation times followed by an intriguing steady state in combination with a compressed exponential correlation function and a temporal heterogeneity.
Journal ArticleDOI
Interplay between Glass Formation and Liquid-Liquid Phase Separation Revealed by the Scattering Invariant.
Stefano Da Vela,Nafisa Begam,Danylo Dyachok,Richard Santiago Schäufele,Olga Matsarskaia,Michal K. Braun,Anita Girelli,Anastasia Ragulskaya,Alessandro Mariani,Fajun Zhang,Frank Schreiber +10 more
TL;DR: This work uses the scattering invariant Q to probe how approaching the glass transition affects the shape of LLPS boundaries in the temperature / volume fraction plane, and non-invasively identifies system-dependent differences for the effect of glass formation on the LLPS boundary.
Journal ArticleDOI
Interplay between Kinetics and Dynamics of Liquid-Liquid Phase Separation in a Protein Solution Revealed by Coherent X-ray Spectroscopy.
Anastasia Ragulskaya,Nafisa Begam,Anita Girelli,Hendrik Rahmann,Mario Reiser,Fabian Westermeier,Michael Sprung,Fajun Zhang,Christian Gutt,Frank Schreiber +9 more
TL;DR: In this paper, the authors used X-ray photon correlation spectroscopy to study the dynamics and kinetics of a protein solution undergoing liquid-liquid phase separation (LLPS) and demonstrated that in the early stage of spinodal decomposition, the kinetics relaxation is up to 40 times slower than the dynamics.
Journal ArticleDOI
Resolving molecular diffusion and aggregation of antibody proteins with megahertz X-ray free-electron laser pulses
Mario Reiser,Anita Girelli,Anastasia Ragulskaya,Sudipta Das,Sharon Berkowicz,Maddalena Bin,Marjorie Ladd-Parada,M. Filianina,Hanna-Friederike Poggemann,Nafisa Begam,Mohammad Sayed Sayed Akhundzadeh,Sonja Timmermann,Lisa Randolph,Yuriy Chushkin,Tilo Seydel,Ulrike Boesenberg,Jörg Hallmann,Johannes Möller,Angel Rodriguez-Fernandez,R. Rosca,Robert Schaffer,Markus Scholz,Roman Shayduk,Alexey Zozulya,Anders Madsen,Frank Schreiber,Fajun Zhang,Fivos Perakis,Christian Gutt +28 more
TL;DR: In this paper , the dynamics of dense antibody protein (Ig-PEG) solutions using megahertz X-ray photon correlation spectroscopy (MHz-XPCS) at the European XFEL were investigated.