Anders Björklund

TL;DR: In this article, the authors used modified rabies virus to trace afferent and efferent connectivity of transplanted human embryonic stem cell (hESC)-derived dopamine neurons in a rat model of Parkinson's disease.

TL;DR: The regrowth of lesioned central acetylcholinesterase (AChE)-positive axons in the adult rat was studied in irides implanted to two different brain sites, and central cholinergic neurones seem partly able to replace the peripheral ones in the reinnervation of a denervated peripheral target.

TL;DR: The combined formaldehyde-ozone reaction and the acidification after the formaldehyde reaction have been successfully applied to tissues incubated with tryptamine, and they provide sensitive and almost selective methods for the detection of tryptamines at the cellular level.

TL;DR: Fluorescence-activated cell sorting procedures are used to isolate mesDA precursors in defined stages of differentiation from mouse ventral mesencephalon (VM) and provide evidence that, during early mesDA neurogenesis, the progenitors for nigral mesDA neurons segregate to lateral parts of the Lmx1a-expressing domain and can be selectively isolated based on their level of Corin expression.

TL;DR: The results demonstrate that unilateral intranigral VM grafts in bilaterally lesioned neonates induce a marked bias in spontaneous- and stress-induced rotation contralateral to the implant not present in the lesion-only controls.