A
Anderson Lo
Publications - 4
Citations - 2969
Anderson Lo is an academic researcher. The author has contributed to research in topics: Copper-free click chemistry & Bioorthogonal chemistry. The author has an hindex of 4, co-authored 4 publications receiving 2724 citations.
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Journal ArticleDOI
Copper-free click chemistry for dynamic in vivo imaging
Jeremy M. Baskin,Jennifer A. Prescher,Scott T. Laughlin,Nicholas J. Agard,Pamela V. Chang,Isaac A. Miller,Anderson Lo,Julian A. Codelli,Carolyn R. Bertozzi +8 more
TL;DR: A Cu-free variant of click chemistry that can label biomolecules rapidly and selectively in living systems, overcoming the intrinsic toxicity of the canonical Cu-catalyzed reaction is reported.
Journal ArticleDOI
A Comparative Study of Bioorthogonal Reactions with Azides
TL;DR: Both the Staudinger ligation and the strain-promoted [3 + 2] cycloaddition using optimized cyclooctynes were effective for tagging azides on live cells and provided a guide for biologists in choosing a suitable ligation chemistry.
Journal ArticleDOI
Copper-free click chemistry in living animals
Pamela V. Chang,Jennifer A. Prescher,Ellen M. Sletten,Jeremy M. Baskin,Isaac A. Miller,Nicholas J. Agard,Anderson Lo,Carolyn R. Bertozzi +7 more
TL;DR: Cu-free click chemistry is established as a bioorthogonal reaction that can be executed in the physiologically relevant context of a mouse for labeling biomolecules in live mice.
Book ChapterDOI
Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics
Scott T. Laughlin,Nicholas J. Agard,Jeremy M. Baskin,Isaac S. Carrico,Pamela V. Chang,Anjali S. Ganguli,Matthew J. Hangauer,Anderson Lo,Jennifer A. Prescher,Carolyn R. Bertozzi +9 more
TL;DR: A recently developed technology, termed metabolic oligosaccharide engineering, enables glycan labeling with probes for visualization in cells and living animals, and enrichment of specific glycoconjugate types for proteomic analysis.