A
Andras Fiser
Researcher at Albert Einstein College of Medicine
Publications - 139
Citations - 14919
Andras Fiser is an academic researcher from Albert Einstein College of Medicine. The author has contributed to research in topics: Protein structure & Peptide sequence. The author has an hindex of 46, co-authored 127 publications receiving 13520 citations. Previous affiliations of Andras Fiser include Alfréd Rényi Institute of Mathematics & Yeshiva University.
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Journal ArticleDOI
Comparative protein structure modeling of genes and genomes
Marc A. Marti-Renom,Ashley C. Stuart,Andras Fiser,Roberto Sanchez,Francisco Melo,Andrej Sali +5 more
TL;DR: There is a need to develop an automated, rapid, robust, sensitive, and accurate comparative modeling pipeline applicable to whole genomes and to encourage new kinds of applications for the many resulting models, based on their large number and completeness at the level of the family, organism, or functional network.
Journal ArticleDOI
Modeling of loops in protein structures.
TL;DR: A new automated modeling technique that significantly improves the accuracy of loop predictions in protein structures by predicting loops of known structure in only approximately correct environments with errors typical of comparative modeling without misalignment is described.
Book ChapterDOI
Modeller: generation and refinement of homology-based protein structure models.
Andras Fiser,Andrej Sali +1 more
TL;DR: This work states that functional characterization of a protein sequence is one of the most frequent problems in biology and comparative or homology modeling can sometimes provide a useful 3D model for a protein (target) that is related to at least one known protein structure (template).
Journal ArticleDOI
Protein production and purification.
Susanne Gräslund,Pär Nordlund,J Weigelt,B M Hallberg,James E. Bray,Opher Gileadi,Stefan Knapp,Udo Oppermann,Cheryl H. Arrowsmith,Raymond Hui,J Ming,Sirano Dhe-Paganon,Park H-W.,Alexei Savchenko,Adelinda Yee,Aled M. Edwards,Renaud Vincentelli,Christian Cambillau,R Kim,Kim S-H.,Zihe Rao,Yunyu Shi,Thomas C. Terwilliger,Kim C-Y.,Hung L-W.,Geoffrey S. Waldo,Yoav Peleg,Shira Albeck,Tamar Unger,Orly Dym,Jaime Prilusky,Joel L. Sussman,Raymond C. Stevens,Scott A. Lesley,Scott A. Lesley,Ian A. Wilson,Ian A. Wilson,Andrzej Joachimiak,Frank R. Collart,Irina Dementieva,Mark I. Donnelly,William H. Eschenfeldt,Youngchang Kim,Lucy Stols,Ruiying Wu,M. Zhou,Stephen K. Burley,J.S. Emtage,J.M. Sauder,D.A. Thompson,Kevin Bain,John G. Luz,Tarun Gheyi,F Zhang,Shane Atwell,Steven C. Almo,Jeffrey B. Bonanno,Andras Fiser,Soumya Swaminathan,F.W. Studier,Mark R. Chance,Andrej Sali,Thomas Acton,Rong Xiao,L Zhao,L C Ma,John F. Hunt,Liang Tong,Kellie Cunningham,Masayori Inouye,Stephen Anderson,Haleema Janjua,Ritu Shastry,C K Ho,D Wang,Hao Wang,M Jiang,Gaetano T. Montelione,David I. Stuart,Raymond J. Owens,S Daenke,Anja Schütz,Udo Heinemann,S Yokoyama,Konrad Büssow,Kristin C. Gunsalus,Kristin C. Gunsalus +86 more
TL;DR: This review presents methods that could be applied at the outset of any project, a prioritized list of alternate strategies and a list of pitfalls that trip many new investigators.
Journal ArticleDOI
ModLoop: automated modeling of loops in protein structures
Andras Fiser,Andrej Sali +1 more
TL;DR: ModLoop is a web server for automated modeling of loops in protein structures that predicts the loop conformations by satisfaction of spatial restraints, without relying on a database of known protein structures.