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André Spiegel
Researcher at Pasteur Institute
Publications - 73
Citations - 2348
André Spiegel is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Malaria & Plasmodium falciparum. The author has an hindex of 25, co-authored 72 publications receiving 2214 citations. Previous affiliations of André Spiegel include Institute of Tropical Medicine Antwerp.
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Combating malaria in Africa.
TL;DR: The impact of chloroquine resistance on the burden of malaria is analyzed and its implications for the Roll Back Malaria initiative are examined.
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Increased frequency of malaria attacks in subjects co-infected by intestinal worms and Plasmodium falciparum malaria.
TL;DR: Results suggest that, compared with those infected, individuals free of helminths had the same degree of protection against malaria as that provided by sickle-cell trait, the most potent factor of resistance to malaria identified to date.
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5. Variation of Plasmodium falciparum msp1 block 2 and msp2 allele prevalence and of infection complexity in two neighbouring Senegalese villages with different transmission conditions
Lassana Konaté,Joanna Zwetyenga,Christophe Rogier,Emmanuel Bischoff,Didier Fontenille,Adama Tall,André Spiegel,Jean-François Trape,Odile Mercereau-Puijalon +8 more
TL;DR: The influence of age on the complexity of asymptomatic malaria infections in a holoendemic area confirmed and substantiates the interpretation that the number of parasite types per isolate reflects acquired antiparasite immunity.
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The rise and fall of malaria in a west African rural community, Dielmo, Senegal, from 1990 to 2012: a 22 year longitudinal study
Jean-François Trape,Adama Tall,Cheikh Sokhna,Alioune Badara Ly,Nafissatou Diagne,Ousmane Ndiath,Catherine Mazenot,Vincent Richard,Abdoulaye Badiane,Fambaye Dieye-Ba,Joseph Faye,Gora Ndiaye,Fatoumata Diene Sarr,Clémentine Roucher,Charles Bouganali,Hubert Bassene,Aissatou Toure-Balde,Christian Roussilhon,Ronald Perraut,André Spiegel,Jean-Louis Sarthou,Luiz Pereira da Silva,Odile Mercereau-Puijalon,Pierre Druilhe,Christophe Rogier +24 more
TL;DR: Rapid decline of clinical immunity allows rapid detection and treatment of novel infections and thus has a key role in sustaining effectiveness of combining artemisinin-based combination therapy and ITNs despite increasing pyrethroid resistance.
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Increased Susceptibility to Malaria during the Early Postpartum Period
Nafissatou Diagne,Christophe Rogier,Cheikh Sokhna,Adama Tall,Didier Fontenille,Christian Roussilhon,André Spiegel,Jean-François Trape +7 more
TL;DR: Among women who live in areas with high rates of transmission of malaria, the susceptibility to malaria is highest during the second and third trimesters of pregnancy and the early postpartum period.