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Andreas Pfeiffer

Bio: Andreas Pfeiffer is an academic researcher from CERN. The author has contributed to research in topics: Large Hadron Collider & Lepton. The author has an hindex of 149, co-authored 1756 publications receiving 131080 citations. Previous affiliations of Andreas Pfeiffer include Heidelberg University & Paul Scherrer Institute.


Papers
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Journal ArticleDOI
S. Agostinelli1, John Allison2, K. Amako3, J. Apostolakis4, Henrique Araujo5, P. Arce4, Makoto Asai6, D. Axen4, S. Banerjee7, G. Barrand, F. Behner4, Lorenzo Bellagamba8, J. Boudreau9, L. Broglia10, A. Brunengo8, H. Burkhardt4, Stephane Chauvie, J. Chuma11, R. Chytracek4, Gene Cooperman12, G. Cosmo4, P. V. Degtyarenko13, Andrea Dell'Acqua4, G. Depaola14, D. Dietrich15, R. Enami, A. Feliciello, C. Ferguson16, H. Fesefeldt4, Gunter Folger4, Franca Foppiano, Alessandra Forti2, S. Garelli, S. Gianì4, R. Giannitrapani17, D. Gibin4, J. J. Gomez Y Cadenas4, I. González4, G. Gracia Abril4, G. Greeniaus18, Walter Greiner15, Vladimir Grichine, A. Grossheim4, Susanna Guatelli, P. Gumplinger11, R. Hamatsu19, K. Hashimoto, H. Hasui, A. Heikkinen20, A. S. Howard5, Vladimir Ivanchenko4, A. Johnson6, F.W. Jones11, J. Kallenbach, Naoko Kanaya4, M. Kawabata, Y. Kawabata, M. Kawaguti, S.R. Kelner21, Paul R. C. Kent22, A. Kimura23, T. Kodama24, R. P. Kokoulin21, M. Kossov13, Hisaya Kurashige25, E. Lamanna26, Tapio Lampén20, V. Lara4, Veronique Lefebure4, F. Lei16, M. Liendl4, W. S. Lockman, Francesco Longo27, S. Magni, M. Maire, E. Medernach4, K. Minamimoto24, P. Mora de Freitas, Yoshiyuki Morita3, K. Murakami3, M. Nagamatu24, R. Nartallo28, Petteri Nieminen28, T. Nishimura, K. Ohtsubo, M. Okamura, S. W. O'Neale29, Y. Oohata19, K. Paech15, J Perl6, Andreas Pfeiffer4, Maria Grazia Pia, F. Ranjard4, A.M. Rybin, S.S Sadilov4, E. Di Salvo8, Giovanni Santin27, Takashi Sasaki3, N. Savvas2, Y. Sawada, Stefan Scherer15, S. Sei24, V. Sirotenko4, David J. Smith6, N. Starkov, H. Stoecker15, J. Sulkimo20, M. Takahata23, Satoshi Tanaka30, E. Tcherniaev4, E. Safai Tehrani6, M. Tropeano1, P. Truscott31, H. Uno24, L. Urbán, P. Urban32, M. Verderi, A. Walkden2, W. Wander33, H. Weber15, J.P. Wellisch4, Torre Wenaus34, D.C. Williams, Douglas Wright6, T. Yamada24, H. Yoshida24, D. Zschiesche15 
TL;DR: The Gelfant 4 toolkit as discussed by the authors is a toolkit for simulating the passage of particles through matter, including a complete range of functionality including tracking, geometry, physics models and hits.
Abstract: G eant 4 is a toolkit for simulating the passage of particles through matter. It includes a complete range of functionality including tracking, geometry, physics models and hits. The physics processes offered cover a comprehensive range, including electromagnetic, hadronic and optical processes, a large set of long-lived particles, materials and elements, over a wide energy range starting, in some cases, from 250 eV and extending in others to the TeV energy range. It has been designed and constructed to expose the physics models utilised, to handle complex geometries, and to enable its easy adaptation for optimal use in different sets of applications. The toolkit is the result of a worldwide collaboration of physicists and software engineers. It has been created exploiting software engineering and object-oriented technology and implemented in the C++ programming language. It has been used in applications in particle physics, nuclear physics, accelerator design, space engineering and medical physics.

18,904 citations

Journal ArticleDOI
TL;DR: In this paper, results from searches for the standard model Higgs boson in proton-proton collisions at 7 and 8 TeV in the CMS experiment at the LHC, using data samples corresponding to integrated luminosities of up to 5.8 standard deviations.

8,857 citations

Journal ArticleDOI
TL;DR: GeGeant4 as mentioned in this paper is a software toolkit for the simulation of the passage of particles through matter, it is used by a large number of experiments and projects in a variety of application domains, including high energy physics, astrophysics and space science, medical physics and radiation protection.
Abstract: Geant4 is a software toolkit for the simulation of the passage of particles through matter. It is used by a large number of experiments and projects in a variety of application domains, including high energy physics, astrophysics and space science, medical physics and radiation protection. Its functionality and modeling capabilities continue to be extended, while its performance is enhanced. An overview of recent developments in diverse areas of the toolkit is presented. These include performance optimization for complex setups; improvements for the propagation in fields; new options for event biasing; and additions and improvements in geometry, physics processes and interactive capabilities

6,063 citations

Journal ArticleDOI
Josée Dupuis1, Josée Dupuis2, Claudia Langenberg, Inga Prokopenko3  +336 moreInstitutions (82)
TL;DR: It is demonstrated that genetic studies of glycemic traits can identify type 2 diabetes risk loci, as well as loci containing gene variants that are associated with a modest elevation in glucose levels but are not associated with overt diabetes.
Abstract: Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic traits, we performed meta-analyses of 21 genome-wide association studies informative for fasting glucose, fasting insulin and indices of beta-cell function (HOMA-B) and insulin resistance (HOMA-IR) in up to 46,186 nondiabetic participants. Follow-up of 25 loci in up to 76,558 additional subjects identified 16 loci associated with fasting glucose and HOMA-B and two loci associated with fasting insulin and HOMA-IR. These include nine loci newly associated with fasting glucose (in or near ADCY5, MADD, ADRA2A, CRY2, FADS1, GLIS3, SLC2A2, PROX1 and C2CD4B) and one influencing fasting insulin and HOMA-IR (near IGF1). We also demonstrated association of ADCY5, PROX1, GCK, GCKR and DGKB-TMEM195 with type 2 diabetes. Within these loci, likely biological candidate genes influence signal transduction, cell proliferation, development, glucose-sensing and circadian regulation. Our results demonstrate that genetic studies of glycemic traits can identify type 2 diabetes risk loci, as well as loci containing gene variants that are associated with a modest elevation in glucose levels but are not associated with overt diabetes.

2,022 citations

Journal ArticleDOI
Georges Aad1, Brad Abbott2, Jalal Abdallah3, Ovsat Abdinov4  +5117 moreInstitutions (314)
TL;DR: A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H→γγ and H→ZZ→4ℓ decay channels.
Abstract: A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H→γγ and H→ZZ→4l decay channels. The results are obtained from a simultaneous fit to the reconstructed invariant mass peaks in the two channels and for the two experiments. The measured masses from the individual channels and the two experiments are found to be consistent among themselves. The combined measured mass of the Higgs boson is mH=125.09±0.21 (stat)±0.11 (syst) GeV.

1,567 citations


Cited by
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[...]

08 Dec 2001-BMJ
TL;DR: There is, I think, something ethereal about i —the square root of minus one, which seems an odd beast at that time—an intruder hovering on the edge of reality.
Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

33,785 citations

Journal ArticleDOI
01 Apr 1988-Nature
TL;DR: In this paper, a sedimentological core and petrographic characterisation of samples from eleven boreholes from the Lower Carboniferous of Bowland Basin (Northwest England) is presented.
Abstract: Deposits of clastic carbonate-dominated (calciclastic) sedimentary slope systems in the rock record have been identified mostly as linearly-consistent carbonate apron deposits, even though most ancient clastic carbonate slope deposits fit the submarine fan systems better. Calciclastic submarine fans are consequently rarely described and are poorly understood. Subsequently, very little is known especially in mud-dominated calciclastic submarine fan systems. Presented in this study are a sedimentological core and petrographic characterisation of samples from eleven boreholes from the Lower Carboniferous of Bowland Basin (Northwest England) that reveals a >250 m thick calciturbidite complex deposited in a calciclastic submarine fan setting. Seven facies are recognised from core and thin section characterisation and are grouped into three carbonate turbidite sequences. They include: 1) Calciturbidites, comprising mostly of highto low-density, wavy-laminated bioclast-rich facies; 2) low-density densite mudstones which are characterised by planar laminated and unlaminated muddominated facies; and 3) Calcidebrites which are muddy or hyper-concentrated debrisflow deposits occurring as poorly-sorted, chaotic, mud-supported floatstones. These

9,929 citations

01 Jan 2014
TL;DR: These standards of care are intended to provide clinicians, patients, researchers, payors, and other interested individuals with the components of diabetes care, treatment goals, and tools to evaluate the quality of care.
Abstract: XI. STRATEGIES FOR IMPROVING DIABETES CARE D iabetes is a chronic illness that requires continuing medical care and patient self-management education to prevent acute complications and to reduce the risk of long-term complications. Diabetes care is complex and requires that many issues, beyond glycemic control, be addressed. A large body of evidence exists that supports a range of interventions to improve diabetes outcomes. These standards of care are intended to provide clinicians, patients, researchers, payors, and other interested individuals with the components of diabetes care, treatment goals, and tools to evaluate the quality of care. While individual preferences, comorbidities, and other patient factors may require modification of goals, targets that are desirable for most patients with diabetes are provided. These standards are not intended to preclude more extensive evaluation and management of the patient by other specialists as needed. For more detailed information, refer to Bode (Ed.): Medical Management of Type 1 Diabetes (1), Burant (Ed): Medical Management of Type 2 Diabetes (2), and Klingensmith (Ed): Intensive Diabetes Management (3). The recommendations included are diagnostic and therapeutic actions that are known or believed to favorably affect health outcomes of patients with diabetes. A grading system (Table 1), developed by the American Diabetes Association (ADA) and modeled after existing methods, was utilized to clarify and codify the evidence that forms the basis for the recommendations. The level of evidence that supports each recommendation is listed after each recommendation using the letters A, B, C, or E.

9,618 citations

Journal ArticleDOI
Georges Aad1, T. Abajyan2, Brad Abbott3, Jalal Abdallah4  +2964 moreInstitutions (200)
TL;DR: In this article, a search for the Standard Model Higgs boson in proton-proton collisions with the ATLAS detector at the LHC is presented, which has a significance of 5.9 standard deviations, corresponding to a background fluctuation probability of 1.7×10−9.

9,282 citations