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Andreas Zaucker
Researcher at University of Birmingham
Publications - 11
Citations - 471
Andreas Zaucker is an academic researcher from University of Birmingham. The author has contributed to research in topics: Zebrafish & Comparative genomics. The author has an hindex of 7, co-authored 10 publications receiving 413 citations. Previous affiliations of Andreas Zaucker include Karlsruhe Institute of Technology.
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Journal ArticleDOI
Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization
Andrew R. Cullinane,Anna Straatman-Iwanowska,Andreas Zaucker,Yoshiyuki Wakabayashi,Christopher K. Bruce,Guanmei Luo,Fatimah Rahman,Figen Gürakan,Eda Utine,Tanju Başarir Özkan,Jonas Denecke,Jurica Vuković,Maja Di Rocco,Hanna Mandel,Hakan Cangul,Hakan Cangul,Randolph P. Matthews,Steve G. Thomas,Joshua Z. Rappoport,Irwin M. Arias,Hartwig Wolburg,A.S. Knisely,Deirdre Kelly,Ferenc Müller,Eamonn R. Maher,Paul Gissen,Paul Gissen +26 more
TL;DR: It is shown that VIPAR forms a functional complex with VPS33B that interacts with RAB11A that has diverse functions in the pathways regulating apical-basolateral polarity in the liver and kidney.
Journal ArticleDOI
Automated high-throughput mapping of promoter-enhancer interactions in zebrafish embryos.
Jochen Gehrig,Markus Reischl,Eva Kalmar,Marco Ferg,Yavor Hadzhiev,Andreas Zaucker,Chengyi Song,Simone Schindler,Urban Liebel,Ferenc Müller +9 more
TL;DR: A high-throughput pipeline for registering domain-specific reporter expression in zebrafish embryos with the aim of mapping the interactions between cis-regulatory modules and core promoters and provides a promoter resource for transgenic reporter studies.
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Developmental regulation of transcription initiation: more than just changing the actors.
TL;DR: The proposed models of transcription initiation by alternative initiation complexes in distinct stages of developmental specialization during vertebrate ontogeny are summarized.
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Genetic disruption of 21-hydroxylase in zebrafish causes interrenal hyperplasia
Helen Eachus,Andreas Zaucker,James A Oakes,Aliesha Griffin,Meltem Weger,Tulay Guran,Angela E Taylor,Abigail Harris,Andy Greenfield,Jonathan L. Quanson,Karl-Heinz Storbeck,Vincent T. Cunliffe,Ferenc Müller,Nils Krone +13 more
TL;DR: This work demonstrates the crucial role of Cyp21a2 in glucocorticoid biosynthesis in zebrafish larvae and establishes an in vivo model allowing studies of systemic consequences of altered steroid hormone synthesis.
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Ferredoxin 1b (Fdx1b) Is the Essential Mitochondrial Redox Partner for Cortisol Biosynthesis in Zebrafish.
Aliesha Griffin,Silvia Parajes,Meltem Weger,Andreas Zaucker,Angela E Taylor,Donna M. O'Neil,Ferenc Müller,Nils Krone +7 more
TL;DR: By using zebrafish, a ferredoxin knockout model system is generated, which demonstrates for the first time the impact of mitochondrial redox regulation on glucocorticoid biosynthesis in vivo.