Author
Andrew C. N. Chen
Other affiliations: Aalborg University, University of Vienna
Bio: Andrew C. N. Chen is an academic researcher from Capital Medical University. The author has contributed to research in topics: Somatosensory evoked potential & Electroencephalography. The author has an hindex of 41, co-authored 122 publications receiving 4162 citations. Previous affiliations of Andrew C. N. Chen include Aalborg University & University of Vienna.
Papers published on a yearly basis
Papers
More filters
TL;DR: A network of spectral EEG activities simultaneously operative at well defined regional fields in the EC state, varying specifically between EC and EO states is depicts, in contrast to transient EEG spectral rhythmic dynamics, current study of long-lasting spectral field powers can characterize state features in EEG.
226 citations
TL;DR: Results suggest that functional activities of certain brain areas might be correlated with the effect of EAS-induced analgesia, in a frequency-dependent dynamic.
206 citations
TL;DR: The LVQ neural network gives the best classification compared with the linear network that uses WH algorithm (the worst), and the non-linear network trained with the LM rule, and it is shown that the automatic recognition algorithm is applicable for distinguishing between alert and drowsy state in recordings that have not been used for the training.
204 citations
TL;DR: The validity tests suggested CHEPs to be useful for research and clinical applications in studying human pain activation related to thermal and nociceptive pathways.
161 citations
TL;DR: The intact skull preparation described here may be used for most longitudinal studies that do not require micron scale resolution and where cortical neural or vascular signals are recorded with intrinsic sensors or in transgenic mice expressing genetically encoded sensors of activity.
161 citations
Cited by
More filters
9,362 citations
TL;DR: A systematic review of the literature regarding how activity in diverse brain regions creates and modulates the experience of acute and chronic pain states, emphasizing the contribution of various imaging techniques to emerging concepts is presented in this paper.
2,686 citations
TL;DR: This review defines the DMN concept with regard to its neuro-anatomy, its functional organisation through low frequency neuronal oscillations, its relation to other recently discovered low frequency resting state networks, and the cognitive functions it is thought to serve, and introduces methodological and analytical issues and challenges.
1,515 citations
TL;DR: This work introduces and clinically examine a new concept of skin treatment called fractional photothermolysis (FP), achieved by applying an array of microscopic treatment zones (MTZ) of thermal injury to the skin.
Abstract: Background and Objectives: We introduce and clinically examine a new concept of skin treatment called fractional photothermolysis (FP), achieved by applying an array of microscopic treatment zones (MTZ) of thermal injury to the skin. Study Design/Materials and Methods: Two prototype devices emitting at 1.5 mm wavelength provided a pattern of micro-exposures with variable MTZ density. Effects of different MTZ densities were tested on the forearms of 15 subjects. Clinical effects and histology were assessed up to 3 months after exposure. Treatment of photoaged skin on the periorbital area in an additional 30 subjects receiving four treatments over a period of 2–3 weeks was also tested. Tissue shrinkage and clinical effects were assessed up to 3 months after treatment. Results: Pattern densities with spacing of 250 mm or more were well tolerated. Typical MTZ had a diameter of 100 mm and penetrated 300 mm into the skin. Reepithelialization was complete within 1 day. Clinical effects were assessed over a 3-month period. Histology at 3 months revealed enhanced undulating rete ridges and increased mucin deposition within the superficial dermis. Periorbital treatments were well tolerated with minimal erythema and edema. Linear shrinkage of 2.1% was measured 3 months after the last treatment. The wrinkle score improved 18% (P < 0.001) 3 months after the last treatment. Conclusions: FP is a new concept for skin restoration treatment. Safety and efficacy were demonstrated with a prototype device. Further clinical studies are necessary to refine the optimum parameters and to explore further dermatological applications. Lasers Surg. Med. 34:426– 438, 2004. 2004 Wiley-Liss, Inc.
1,369 citations
TL;DR: Of tested markers, cyst fluid CEA is the most accurate test available for the diagnosis of mucinous cystic lesions of the pancreas.
1,253 citations