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Andrew D. Rouillard
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 22
Citations - 8894
Andrew D. Rouillard is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Feature selection & Data integration. The author has an hindex of 14, co-authored 22 publications receiving 5763 citations. Previous affiliations of Andrew D. Rouillard include University of Virginia & GlaxoSmithKline.
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Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
Maxim V. Kuleshov,Matthew R. Jones,Andrew D. Rouillard,Nicolas F. Fernandez,Qiaonan Duan,Zichen Wang,Simon Koplev,Sherry L. Jenkins,Kathleen M. Jagodnik,Alexander Lachmann,Michael G. McDermott,Caroline D. Monteiro,Gregory W. Gundersen,Avi Ma'ayan +13 more
TL;DR: A significant update to one of the tools in this domain called Enrichr, a comprehensive resource for curated gene sets and a search engine that accumulates biological knowledge for further biological discoveries is presented.
Journal ArticleDOI
The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins.
Andrew D. Rouillard,Gregory W. Gundersen,Nicolas F. Fernandez,Zichen Wang,Caroline D. Monteiro,Michael G. McDermott,Avi Ma'ayan +6 more
TL;DR: The Harmonizome is a comprehensive resource of knowledge about genes and proteins that enables researchers to discover novel relationships between biological entities, as well as form novel data-driven hypotheses for experimental validation.
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LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures
Qiaonan Duan,Corey Flynn,Mario Niepel,Marc Hafner,Jeremy L. Muhlich,Nicolas F. Fernandez,Andrew D. Rouillard,Christopher M. Tan,Edward Y. Chen,Todd R. Golub,Peter K. Sorger,Aravind Subramanian,Avi Ma'ayan +12 more
TL;DR: LINCS Canvas Browser (LCB) is an interactive HTML5 web-based software application that facilitates querying, browsing and interrogating many of the currently available LINCS L1000 data.
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L1000CDS2: LINCS L1000 characteristic direction signatures search engine
Qiaonan Duan,St. Patrick Reid,Neil R. Clark,Zichen Wang,Nicolas F. Fernandez,Andrew D. Rouillard,Ben Readhead,Sarah R. Tritsch,Rachel A. Hodos,Marc Hafner,Mario Niepel,Peter K. Sorger,Joel T. Dudley,Sina Bavari,Rekha G. Panchal,Avi Ma'ayan +15 more
TL;DR: It is demonstrated that processing the L1000 data with the characteristic direction (CD) method significantly improves signal to noise compared with the MODZ method currently used to compute L1000 signatures.
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Pharos: Collating protein information to shed light on the druggable genome
Dac-Trung Nguyen,Stephen L. Mathias,Cristian Bologa,Søren Brunak,Nicolas F. Fernandez,Anna Gaulton,Anne Hersey,Jayme Holmes,Lars Juhl Jensen,Anneli Karlsson,Guixia Liu,Guixia Liu,Avi Ma'ayan,Geetha Mandava,Subramani Mani,Saurabh Mehta,Saurabh Mehta,John P. Overington,Juhee Patel,Andrew D. Rouillard,Stephan C. Schürer,Timothy Sheils,Anton Simeonov,Larry A. Sklar,Noel Southall,Oleg Ursu,Dusica Vidovic,Anna Waller,Jeremy J. Yang,Ajit Jadhav,Tudor I. Oprea,Rajarshi Guha +31 more
TL;DR: Two resources developed by the IDG Knowledge Management Center are described: the Target Central Resource Database (TCRD) which collates many heterogeneous gene/protein datasets and Pharos (https://pharos.nih.gov), a multimodal web interface that presents the data from TCRD.