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Andrew J. Hughes

Researcher at Barwon Health

Publications -  38
Citations -  7943

Andrew J. Hughes is an academic researcher from Barwon Health. The author has contributed to research in topics: Mycobacterium ulcerans & Buruli ulcer. The author has an hindex of 23, co-authored 36 publications receiving 6928 citations. Previous affiliations of Andrew J. Hughes include University of Melbourne & Geelong Hospital.

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Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013

Mohsen Naghavi, +731 more
- 10 Jan 2015 - 
TL;DR: In the Global Burden of Disease Study 2013 (GBD 2013) as discussed by the authors, the authors used the GBD 2010 methods with some refinements to improve accuracy applied to an updated database of vital registration, survey, and census data.
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Reduced BDNF mRNA expression in the Parkinson's disease substantia nigra.

David W. Howells, +6 more
- 01 Nov 2000 - 
TL;DR: If BDNF is an autocrine/paracrine factor for SNpc dopaminergic neurons, loss of BDNF-expressing neurons may compromise the well-being of their surviving neighbors and neurons expressing particularly low levels ofBDNF mRNA may be those at greatest risk of injury in PD and possibly the trigger for the degeneration itself.
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Voice characteristics in the progression of Parkinson’s disease

Rhonda J. Holmes, +3 more
- 09 Jul 2000 - 
TL;DR: The present data suggested that the PD patients' voices were characterized by excess jitter, a high-speaking fundamental frequency for males and a reduced fundamental frequency variability for females.
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Botulinum toxin A for treatment of upper limb spasticity following stroke: a multi-centre randomized placebo-controlled study of the effects on quality of life and other person-centred outcomes.

Paul McCrory, +9 more
- 01 Jun 2009 - 
TL;DR: Although no change in quality of life was demonstrated using the AQoL, botulinum toxin type A was found to be safe and efficacious in reducing upper limb spasticity and improving the ability to achieve personal goals.
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New dopaminergic neurons in Parkinson's disease striatum

Michelle J. Porritt, +5 more
- 01 Jul 2000 - 
TL;DR: A new population of dopaminergic neurons has been identified in Parkinson's disease striatum and these neurons are sufficiently numerous to have an important effect on dopamine function in the striatum.