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Andrew J. Sullivan
Researcher at University of Massachusetts Medical School
Publications - 4
Citations - 3578
Andrew J. Sullivan is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Signal transduction & Proto-oncogene tyrosine-protein kinase Src. The author has an hindex of 3, co-authored 4 publications receiving 3315 citations. Previous affiliations of Andrew J. Sullivan include Genzyme.
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Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
Antoine E. Karnoub,Ajeeta B. Dash,Annie P. Vo,Andrew J. Sullivan,Mary W. Brooks,George W. Bell,Andrea L. Richardson,Kornelia Polyak,Ross Tubo,Robert A. Weinberg +9 more
TL;DR: It is demonstrated that bone-marrow-derived human mesenchymal stem cells, when mixed with otherwise weakly metastatic human breast carcinoma cells, cause the cancer cells to increase their metastatic potency greatly when this cell mixture is introduced into a subcutaneous site and allowed to form a tumour xenograft.
Journal ArticleDOI
Tyrosine phosphorylation controls Runx2‐mediated subnuclear targeting of YAP to repress transcription
Sayyed K. Zaidi,Andrew J. Sullivan,Ricardo F. Medina,Yoshiaki Ito,Andre J. van Wijnen,Janet L. Stein,Jane B. Lian,Gary S. Stein +7 more
TL;DR: It is suggested that Src/Yes signals are integrated through organization of Runx2–YAP transcriptional complexes at subnuclear sites to attenuate skeletal gene expression.
Journal ArticleDOI
Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites
Sayyed K. Zaidi,Andrew J. Sullivan,Andre J. Van Wijnen,Janet L. Stein,Gary S. Stein,Jane B. Lian +5 more
TL;DR: Runx-mediated intranuclear targeting of Smads is critical for the integration of two distinct pathways essential for fetal development.