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Andrew K. Davey
Researcher at Griffith University
Publications - 97
Citations - 2597
Andrew K. Davey is an academic researcher from Griffith University. The author has contributed to research in topics: Warfarin & Pyocyanin. The author has an hindex of 26, co-authored 94 publications receiving 2197 citations. Previous affiliations of Andrew K. Davey include University of Otago & Monash University, Parkville campus.
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Journal ArticleDOI
Cellular Effects of Pyocyanin, a Secreted Virulence Factor of Pseudomonas aeruginosa.
Susan Hall,Catherine McDermott,Shailendra Anoopkumar-Dukie,Amelia J. McFarland,Amanda Forbes,Anthony V. Perkins,Andrew K. Davey,Russ Chess-Williams,Milton J. Kiefel,Devinder Arora,Gary Grant +10 more
TL;DR: It has been postulated that, given its chemical properties, PCN is able to readily cross biological membranes, however studies have yet to be undertaken to evaluate this effect, and this review highlights the possible manifestations of PCN exposure.
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Silica-lipid hybrid (SLH) microcapsules: a novel oral delivery system for poorly soluble drugs.
TL;DR: It is postulated that SLH microcapsules improve CEL oral absorption via dissolution enhancement, potentially in conjunction with other unexplored mechanisms, hence offering the possibility of dose reduction for improved therapeutic efficacy and cost-effectiveness of poorly soluble drugs.
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Molecular mechanisms underlying the effects of statins in the central nervous system
Amelia J. McFarland,Shailendra Anoopkumar-Dukie,Devinder Arora,Gary Grant,Catherine McDermott,Anthony V. Perkins,Andrew K. Davey +6 more
TL;DR: An updated discussion on the molecular mechanisms contributing to statins’ possible effects on cognitive function, neurodegenerative disease, and various neurological disorders such as stroke, epilepsy, depression and CNS cancers is provided.
Journal ArticleDOI
Surgical adhesions: a timely update, a great challenge for the future.
Andrew K. Davey,Peter Maher +1 more
TL;DR: Strategies to reduce adhesion formation include improving surgical techniques, optimizing laparoscopy conditions, using pharmacologic interventions targeted at the inflammatory response and/or fibrin deposition, and using agents that provide a physical barrier toAdhesion formation.
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Dry hybrid lipid-silica microcapsules engineered from submicron lipid droplets and nanoparticles as a novel delivery system for poorly soluble drugs.
Spomenka Simovic,Peter J Heard,He Hui,Yunmei Song,Frank Peddie,Andrew K. Davey,AC Lewis,Thomas Rades,Clive A. Prestidge +8 more
TL;DR: The hybrid lipid-silica microcapsules improve oral absorption by enhancing lipolysis and drug dissolution and showed the highest maximum plasma concentration (C(max)) among the investigated formulations.