A
Andrew Wragg
Researcher at Queen Mary University of London
Publications - 128
Citations - 5971
Andrew Wragg is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Percutaneous coronary intervention & Myocardial infarction. The author has an hindex of 29, co-authored 119 publications receiving 5028 citations. Previous affiliations of Andrew Wragg include Johns Hopkins University & University College London.
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Journal ArticleDOI
p53 Regulates Mitochondrial Respiration
Satoaki Matoba,Ju Gyeong Kang,Ju Gyeong Kang,Willmar D. Patino,Willmar D. Patino,Andrew Wragg,Andrew Wragg,Manfred Boehm,Manfred Boehm,Oksana Gavrilova,Oksana Gavrilova,Paula J. Hurley,Paula J. Hurley,Fred Bunz,Fred Bunz,Paul M. Hwang,Paul M. Hwang +16 more
TL;DR: It is shown that p53, one of the most frequently mutated genes in cancers, modulates the balance between the utilization of respiratory and glycolytic pathways, and Synthesis of Cytochrome c Oxidase 2 (SCO2) is identified as the downstream mediator of this effect.
Journal ArticleDOI
Myocardial Injury after Noncardiac Surgery: A Large, International, Prospective Cohort Study Establishing Diagnostic Criteria, Characteristics, Predictors, and 30-day Outcomes
Fernando Botto,Pablo Alonso-Coello,Matthew T. V. Chan,Matthew T. V. Chan,Juan Carlos Villar,Denis Xavier,Sadeesh Srinathan,Gordon H. Guyatt,Patricia Cruz,Patricia Cruz,Michelle M. Graham,Michelle M. Graham,Chew Yin Wang,Otavio Berwanger,R.M. Pearse,R.M. Pearse,Bruce M Biccard,Valsa Abraham,Germán Málaga,Germán Málaga,Graham S. Hillis,Graham S. Hillis,Reitze N. Rodseth,Deborah J. Cook,Deborah J. Cook,Deborah J. Cook,Carisi Anne Polanczyk,Wojciech Szczeklik,Daniel I. Sessler,Daniel I. Sessler,Tej Sheth,Tej Sheth,Gareth L Ackland,Gareth L Ackland,Martin Leuwer,Amit X Garg,Amit X Garg,Yannick LeManach,Yannick LeManach,Shirley Pettit,Diane Heels-Ansdell,Giovanna Luratibuse,Giovanna Luratibuse,Michael Walsh,Michael Walsh,Robert Sapsford,Holger J Schünemann,Holger J Schünemann,Andrea Kurz,Andrea Kurz,Sabu Thomas,Marko Mrkobrada,Marko Mrkobrada,Lehana Thabane,Hertzel C. Gerstein,Pilar Paniagua,Pilar Paniagua,Peter Nagele,Peter Nagele,Parminder Raina,Salim Yusuf,Salim Yusuf,Salim Yusuf,Philip J. Devereaux,Philip J. Devereaux,Matthew J. McQueen,Mohit Bhandari,Jackie Bosch,Norman Buckley,Clara K Chow,Richard Halliwell,Stephen Li,Vincent W. Lee,J. Mooney,Mariana Vargas Furtado,Erica Aranha Suzumura,Eliana Vieira Santucci,Katia R. M. Leite,Jose Amalth do Espirirto Santo,César A. Jardim,Alexandre Biasi Cavalcanti,Hélio Penna Guimarães,Michael J Jacka,Finlay A. McAlister,Sean McMurtry,Derek R. Townsend,Neesh Pannu,Sean M. Bagshaw,Amal Bessissow,Emmanuelle Duceppe,John W. Eikelboom,Javier Ganame,James Hankinson,Stephen Hill,Sanjit S. Jolly,Andre Lamy,Elizabeth Ling,Patrick Magloire,Guillaume Paré,Deven Reddy,David Szalay,Jacques G. Tittley,Jeff Weitz,Richard P. Whitlock,Saeed Darvish-Kazim,Justin DeBeer,Peter A. Kavsak,Clive Kearon,Richard Mizera,Martin O'Donnell,Matthew B. McQueen,Jehonathan H. Pinthus,Sebastian Ribas,Marko Simunovic,Vikas Tandon,Tomas VanHelder,Mitchell Winemaker,Sarah D. McDonald,Paul M. O'Bryne,Ameen Patel,James Paul,Zubin Punthakee,Karen Raymer,Omid Salehian,Frederick A. Spencer,Stephen D. Walter,Andrew Worster,Anthony Adili,Catherine M. Clase,Mark Crowther,James D. Douketis,Azim S. Gangji,Paul Jackson,Wendy Lim,Peter Lovrics,Sergio Mazzadi,William Orovan,Jill Rudkowski,Mark Soth,Maria Tiboni,Rey R. Acedillo,Amit Garg,Amit Garg,Ainslie Hildebrand,Ngan N. Lam,Danielle MacNeil,Pavel S Roshanov,Sadeesh K Srinathan,Clare D. Ramsey,Philip St John,Laurel Thorlacius,Faisal Siddiqui,Hilary P Grocott,Andrew McKay,Trevor W R Lee,Ryan J. J. Amadeo,Duane J. Funk,Heather McDonald,James Zacharias,Olga L. Cortés,Maria Stella Chaparro,Skarlett Vásquez,Alvaro Castañeda,Silvia Moreira Ayub Ferreira,Pierre Coriat,Denis Monneret,Jean Pierre Goarin,Cristina Ibanez Esteve,Catherine Royer,Georges Daas,Gordon Y.S. Choi,Tony Gin,Lydia C.W. Lit,Alben Sigamani,Atiya Faruqui,Radhika Dhanpal,Smitha Almeida,Joseph Cherian,Sultana Furruqh,Lalita Afzal,P. George,Shaveta Mala,Holger Schünemann,Holger Schünemann,Paola Muti,Enrico Vizza,Gracie Ong,Marzida Mansor,Alvin S.B. Tan,Ina Ismiarti Shariffuddin,V Vasanthan,Noorjahan Haneem Md Hashim,A. Wahab Undok,Ushananthini Ki,Hou Yee Lai,Wan Azman Ahmad,Azad Hassan Abdul Razack,Vanessa Valderrama-Victoria,Javier D Loza-Herrera,Maria De Los Angeles Lazo,Aida Rotta-Rotta,Barbara Sokołowska,Jacek Musial,Jacek Górka,Paweł Iwaszczuk,Mateusz Kózka,Maciej Chwała,Marcin Raczek,Tomasz Mrowiecki,Bogusz Kaczmarek,B M Biccard,Hussein Cassimjee,Dean Gopalan,Theroshnie Kisten,Aine Mugabi,P. Naidoo,Rubeshan Naidoo,R.N. Rodseth,D.L. Skinner,Alex Torborg,Gerard Urrútia,Mari Luz Maestre,Miquel Santaló,Raúl Gonzalez,Adrià Font,Cecilia Martínez,Xavier Pelaez,Marta De Antonio,José Villamor,Jesús Alvarez García,Maria José Ferré,Ekaterina Popova,Ignacio Garutti,Carmen Fernández,Maria Palencia,Susana Díaz,Teresa Del Castillo,Alberto Varela,Angeles de Miguel,Manuel Muñoz,Patricia Piñeiro,Gabriel Cusati,Maria Del Barrio,Maria José Membrillo,David Orozco,Fidel Reyes,Robert J. Sapsford,Julian H. Barth,Julian Scott,Alistair Hall,Simon J. Howell,Michaela Lobley,Janet Woods,Susannah Howard,Joanne Fletcher,Nikki Dewhirst,C. Williams,A. Rushton,Ingeborg Welters,M Leuwer,Rupert Pearse,Rupert Pearse,G.L. Ackland,G.L. Ackland,Ahsun Khan,Edyta Niebrzegowska,Sally Benton,Andrew Wragg,Andrew Archbold,Amanda Smith,Eleanor McAlees,Cheryl Ramballi,Neil MacDonald,Marta Januszewska,Robert C M Stephens,Anna Reyes,Laura Gallego Paredes,Pervez Sultan,David Cain,John Whittle,Ana Gutierrez del Arroyo,Zhuo Sun,Patrick S Finnegan,Cameron Egan,Hooman Honar,Aram Shahinyan,Krit Panjasawatwong,Alexander Y. Fu,Sihe Wang,Edmunds Reineks,Jane Blood,Megan Kalin,David W. Gibson,Troy S. Wildes,Vascular Events In Noncardiac Surgery Patients Cohort Evaluation (Vision) Investigators +294 more
TL;DR: Among adults undergoing noncardiac surgery, MINS was an independent predictor of 30-day mortality and had the highest population-attributable risk of the perioperative complications.
Journal ArticleDOI
A rapid protocol for the prevention of contrast-induced renal dysfunction: the RAPPID study.
Christopher S. Baker,Andrew Wragg,Sanjay Kumar,Rodney De Palma,Laurence R.I. Baker,Charles Knight +5 more
TL;DR: Oral acetylcysteine should be considered in all patients at risk of RCIN before contrast exposure when time constraints preclude adequate oral prophylaxis, provided the patient is able to tolerate this degree of volume loading.
Journal ArticleDOI
TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling.
Brian C. Cooley,Jose B. Nevado,Jose B. Nevado,Jason A. Mellad,Dan Yang,Cynthia St. Hilaire,Alejandra Negro,Fang Fang,Guibin Chen,Hong San,Avram D. Walts,Robin Schwartzbeck,Brandi Taylor,Jan D. Lanzer,Andrew Wragg,Andrew Wragg,Abdalla Elagha,Abdalla Elagha,Leilani E. Beltran,Colin Berry,Colin Berry,Robert Feil,Renu Virmani,Elena Ladich,Jason C. Kovacic,Jason C. Kovacic,Manfred Boehm +26 more
TL;DR: It is established that EndMT is an important mechanism underlying neointimal formation in interpositional vein grafts, and identifies the TGF-β–Smad2/3–Slug signaling pathway as a potential therapeutic target to prevent clinical vein graft stenosis.
Journal ArticleDOI
Implementing workplace-based assessment across the medical specialties in the United Kingdom
TL;DR: To evaluate the reliability and feasibility of assessing the performance of medical specialist registrars (SpRs) using three methods: the mini‐clinical evaluation exercise, directly observed procedural skills (DOPS) and multi‐source feedback (MSF) to help inform annual decisions about the outcome of SpR training.