Author
Anil Saxena
Bio: Anil Saxena is an academic researcher from University of Rajasthan. The author has contributed to research in topics: Trigonal bipyramidal molecular geometry & Tin. The author has an hindex of 9, co-authored 13 publications receiving 344 citations.
Papers
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TL;DR: In this article, the properties of five and six-coordinated di and tri-n-butyl tin(IV) semi-and thio-semi carbazates have been characterized by IR, NMR, and Mass spectroscopy.
76 citations
TL;DR: In this paper, four tin(IV) complexes of tridentate dithiocarbazate Schiff bases have been synthesized and characterized by their elemental analyses and UV, IR, 1H NMR, and Mossbauer spectroscopies and X-ray powder diffraction.
62 citations
TL;DR: Some five and six-coordinated di-and tri-n-butyl tin(IV) complexes have been synthesized and characterised on the basis of microanalyses, molecular weight determinations, IR, NMR (1H, 13C, 119Sn) and 119Sn Mossbauer spectroscopy as mentioned in this paper.
41 citations
TL;DR: In this paper, the synthesis, characterization and geometrical features of pentacoordinated dibutyltin(IV) dithiocarbazate complexes are described.
35 citations
TL;DR: Di-n-butyltin complex derived from salicylaldehyde-S-methyl dithiocarbazate has been found to be the most active in this series and display T/C values in the range 94-124.
32 citations
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TL;DR: In this article, the authors reviewed the literature on organotin(IV) complexes taking into account the biological aspects of the complexes discussed and provided useful information about the structure and stabilities of the complex formed.
544 citations
TL;DR: In this article, the shape of coordination polyhedra of di-n-butyltin(IV) compounds and their complexes in coordinating and non-coordinating solvents was described from analysis of their δ(119Sn) and 1J(119sn-13C) parameters.
494 citations
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TL;DR: In this paper, the compilation and updation of 119Sn chemical shifts (δ 119Sn) from studies on organotin compound and inorganic tin compounds, indirect nuclear spin-spin couplings, relaxation mechanisms concerning the 119Sn nucleus, and experimental details for 1I9Sn-NMR measurements are discussed.
Abstract: Publisher Summary Tin (Sn) compounds are well-recognized both in basic research and in industrial applications. Tin NMR spectroscopy includes three magnetically active tin isotopes namely, 115Sn, 117Sn , and l19Sn. However, most tin NMR parameters refer to the 119Sn nucleus owing to its properties such as abundance, magnetic moment, and NMR frequency. This chapter describes: (1) the compilation and updation of 119Sn chemical shifts (δ 119Sn) from studies on organotin compound and inorganic tin compounds, (2) indirect nuclear spin-spin couplings, (3) relaxation mechanisms concerning the 119Sn nucleus, and (4) experimental details for 1I9Sn-NMR measurements. It is observed that with modem equipment there are, in principle, no serious experimental difficulties in observing 119Sn resonances either directly or by heteronuclear double resonance. δ 119Sn data, available for all kinds of tin compounds, significantly allows using this parameter in an empirical way in order to find models for the qualitative interpretation of δ 119Sn. This also applies to couplings involving the l19Sn nucleus, which serve as a sensitive tool in the discussion of structure and bonding. All 119Sn-NMR parameters of tin compounds largely concern measurements in the liquid state.
461 citations
230 citations
TL;DR: It is concluded that chlorpyrifos induces severe testicular damage and results in reduction in sperm count and thus affect fertility, and application of such insecticide should be limited to a designed programme.
Abstract: Organophosphates are among the most widely used synthetic insect pesticides. The widespread use of organophosphates has stimulated research into the possible existence of effects related with their reproductive toxic activity. Present study was therefore, undertaken to assess the effects of chlorpyrifos on testes, the main organ of male reproduction. Chlorpyrifos at the dose levels of 7.5, 12.5 and 17.5 mg/kg b. wt./day was administered orally to male rats of Wistar strain for 30 days to evaluate the toxic alterations in testicular histology, biochemistry, sperm dynamics and testosterone levels. The body weight of animals did not show any significant change, however, a significant reduction was observed in testes. Chlorpyrifos also brought about marked reduction in epididymal and testicular sperm counts in exposed males and a decrease in serum testosterone concentration. Histopathological examination of testes showed mild to severe degenerative changes in seminiferous tubules at various dose levels. Fertility test showed 85% negative results. A significant reduction in the sialic acid content of testes and testicular glycogen was noticed, whereas the protein and cholesterol content was raised at significant levels. All these toxic effects are moderate at low doses and become severe at higher dose levels. From the results of the present study it is concluded that chlorpyrifos induces severe testicular damage and results in reduction in sperm count and thus affect fertility. Small changes in sperm counts are known to have adverse affects on human fertility. Therefore, application of such insecticide should be limited to a designed programme.
184 citations