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Author

Anila Fariq

Bio: Anila Fariq is an academic researcher. The author has contributed to research in topics: Ecology (disciplines). The author has an hindex of 1, co-authored 1 publications receiving 3 citations.

Papers
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Dissertation
01 Jan 2019
TL;DR: 137 7.2.3 Oxidation of iron by Acidithiobacillus ferrooxidans IO-2C in the presence of different iron substrates 139 6.3 Discussion 150 Chapter 8: Culture independent microbial diversity of extremophiles 152 Abstract 152 8.2 results 8.3 discussion 168 Chapter 9: Discussion 171 Conclusion 187 References 188
Abstract: 137 7.1 Background 137 7.2 Results 138 7.2.1 Isolation of acidophilic bacteria 138 7.2.2 Molecular characterization 138 7.2.3 Oxidation of iron by Acidithiobacillus ferrooxidans IO-2C in the presence of different iron substrates 139 7.2.4 Draft genome of Acidithiobacillus ferrooxidans IO-2C 144 7.3 Discussion 150 Chapter 8: Culture independent microbial diversity of extremophiles 152 Abstract 152 8.1 Background 152 8.2 Results 153 8.2.1 Microbial diversity of hot spring 153 8.2.2 Microbial diversity of saline soil 157 8.2.3 Microbial diversity of acid seep 162 8.3 Discussion 168 Chapter 9: Discussion 171 Conclusion 187 References 188

3 citations


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01 Jan 2009
TL;DR: In this article, the diversity and ecophysiology of Rhodocyclales in activated sludge from a full-scale wastewater treatment plant were analyzed following a holistic strategy based on the isotope array approach, which allows for a parallel functional probing of different phylogenetic groups.
Abstract: Extensive physiological analyses of different microbial community members in many samples are difficult because of the restricted number of target populations that can be investigated in reasonable time by standard substrate-mediated isotope-labeling techniques. The diversity and ecophysiology of Rhodocyclales in activated sludge from a full-scale wastewater treatment plant were analyzed following a holistic strategy based on the isotope array approach, which allows for a parallel functional probing of different phylogenetic groups. Initial diagnostic microarray, comparative 16S rRNA gene sequence, and quantitative fluorescence in situ hybridization surveys indicated the presence of a diverse community, consisting of an estimated number of 27 operational taxonomic units that grouped in at least seven main Rhodocyclales lineages. Substrate utilization profiles of probe-defined populations were determined by radioactive isotope array analysis and microautoradiography-fluorescence in situ hybridization of activated sludge samples that were briefly exposed to different substrates under oxic and anoxic, nitrate-reducing conditions. Most detected Rhodocyclales groups were actively involved in nitrogen transformation, but varied in their consumption of propionate, butyrate, or toluene, and thus in their ability to use different carbon sources in activated sludge. This indicates that the functional redundancy of nitrate reduction and the functional versatility of substrate usage are important factors governing niche overlap and differentiation of diverse Rhodocyclales members in this activated sludge.

87 citations

Journal Article
TL;DR: The potential applications of extremolytes are being investigated for human therapeutics including anticancer drugs, antioxidants, cell cycle blocking agents, anticholesteric drugs, etc as discussed by the authors.
Abstract: Micro‐organisms with the ability to survive in extreme environmental conditions are known as ‘extremophiles’. Currently, extremophiles have caused a sensation in the biotechnology/pharmaceutical industries with their novel compounds, known as ‘extremolytes’. The potential applications of extremolytes are being investigated for human therapeutics including anticancer drugs, antioxidants, cell cycle‐blocking agents, anticholesteric drugs, etc. It is hypothesized that the majority of ultraviolet radiation (UVR)‐resistant micro‐organisms can be used to develop anticancer drugs to prevent skin damage from UVR. The metabolites from UVR‐resistant microbes are a great source of potential therapeutic applications in humans. This article aims to discuss the potentials of extremolytes along with their therapeutic implications of UVR extremophiles. The major challenges of therapeutic development using extremophiles are also discussed.

5 citations

Journal ArticleDOI
07 Feb 2017
TL;DR: It is shown that some particular salts or their combinations may have impact on higher growth of Geobacillus sp.
Abstract: In this study we determined that Geobacillus sp. 15 strain secretes antibacterial compound-bacteriocin. Only few bacteriocin producing thermophilic bacteria of this genus have been identified to the date. Also, we optimized medium composition for the better cell growth of this strain and increased the yield of secreted bacteriocin. In this work we showed that some particular salts or their combinations may have impact on higher growth of Geobacillus sp. 15 strain bacteria or their produced bacteriocins. These results can facilitate research on this strain and its secreted bacteriocin. These antibacterial proteins and peptides are promising natural agents as an alternative to antibiotics in medicine or veterinary and to traditional preservatives in food industry. Optimized composition of the growth medium can be very useful for studies of other Geobacillus spp. strains and their produced bacteriocins. Furthermore, these data may be used to increase the biomass of Geobacillus bacteria and the yield of protein when it is dependent on bacterial cell yield.

2 citations