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Anirban Siddhanta
Researcher at University of Calcutta
Publications - 21
Citations - 1004
Anirban Siddhanta is an academic researcher from University of Calcutta. The author has contributed to research in topics: Golgi apparatus & Phosphatidic acid. The author has an hindex of 11, co-authored 17 publications receiving 967 citations. Previous affiliations of Anirban Siddhanta include Albert Einstein College of Medicine.
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Journal ArticleDOI
Phospholipase D Stimulates Release of Nascent Secretory Vesicles from the trans-Golgi Network
Ye-Guang Chen,Anirban Siddhanta,Cary D. Austin,Scott M. Hammond,Tsung Chang Sung,Michael A. Frohman,Andrew J. Morris,Dennis Shields +7 more
TL;DR: It is demonstrated that immunoaffinity-purified human PLD1 stimulated nascent secretory vesicle budding from the TGN and ARF-1 stimulated endogenous PLD activity in Golgi membranes approximately threefold and this activation correlated with its enhancement of vesicles budding.
Journal ArticleDOI
Intracellular Localization of Phospholipase D1 in Mammalian Cells
Zachary Freyberg,David A. Sweeney,Anirban Siddhanta,Sylvain G. Bourgoin,Michael A. Frohman,Dennis Shields +5 more
TL;DR: The data show that the intracellular localization of PLD1 is consistent with a role in vesicle trafficking from the Golgi apparatus and suggest that it also functions in the cell nucleus.
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Secretory Vesicle Budding from the Trans-Golgi Network Is Mediated by Phosphatidic Acid Levels *
Anirban Siddhanta,Dennis Shields +1 more
TL;DR: The data demonstrate that in mammalian cells accumulation of PA rather than DAG is a key step in regulating budding of secretory vesicles from the trans-Golgi network.
Journal ArticleDOI
Inhibition of phosphatidic acid synthesis alters the structure of the Golgi apparatus and inhibits secretion in endocrine cells.
TL;DR: The results suggest that PA stimulation of PtdIns(4,5)P2 synthesis is required for maintaining the structural integrity and function of the Golgi apparatus.
Journal ArticleDOI
"Slip, sliding away": phospholipase D and the Golgi apparatus.
TL;DR: Recent observations on PLD localization to the Golgi apparatus are discussed and how members of this enzyme family might play a role in regulating the structure of this organelle.