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Anita K. McElroy
Researcher at University of Pittsburgh
Publications - 82
Citations - 4766
Anita K. McElroy is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Ebola virus & Virus. The author has an hindex of 31, co-authored 74 publications receiving 3731 citations. Previous affiliations of Anita K. McElroy include Emory University & Emory University Hospital.
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Journal ArticleDOI
Animal models for COVID-19.
César Muñoz-Fontela,William E. Dowling,Simon G. P. Funnell,Pierre Stéphane Gsell,A. Ximena Riveros-Balta,Randy A. Albrecht,Hanne Leth Andersen,Ralph S. Baric,Miles W. Carroll,Marco Cavaleri,Chuan Qin,Ian Crozier,Kai Dallmeier,Leon de Waal,Emmie de Wit,Leen Delang,Erik D. Dohm,W. Paul Duprex,Darryl Falzarano,Courtney L. Finch,Matthew B. Frieman,Barney S. Graham,Lisa E. Gralinski,Kate Guilfoyle,Bart L. Haagmans,Geraldine A. Hamilton,Amy L. Hartman,Sander Herfst,Suzanne J.F. Kaptein,William B. Klimstra,Ivana Knezevic,Philip R. Krause,Jens H. Kuhn,Roger Le Grand,Mark G. Lewis,Wen-Chun Liu,Pauline Maisonnasse,Anita K. McElroy,Vincent J. Munster,Nadia Oreshkova,Angela L. Rasmussen,Joana Rocha-Pereira,Barry Rockx,Estefanía Rodríguez,Thomas F. Rogers,Francisco J. Salguero,Michael Schotsaert,Koert J. Stittelaar,Hendrik Jan Thibaut,Chien Te K. Tseng,Júlia Vergara-Alert,Martin Beer,Trevor Brasel,Jasper Fuk-Woo Chan,Adolfo García-Sastre,Johan Neyts,Stanley Perlman,Douglas S. Reed,Juergen A. Richt,Chad J. Roy,Joaquim Segalés,Seshadri S. Vasan,Seshadri S. Vasan,Ana Maria Henao-Restrepo,Dan H. Barouch +64 more
TL;DR: The findings of a World Health Organization expert working group that is developing animal models to test vaccines and therapeutic agents for the treatment of COVID-19, and their relevance for preclinical testing, are reviewed.
Journal ArticleDOI
Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase
Salme Taagepera,David McDonald,Jonathan E. Loeb,Laura L. Whitaker,Anita K. McElroy,Jean Y. J. Wang,Thomas J. Hope +6 more
TL;DR: Results demonstrate that c-Abl shuttles continuously between the nucleus and the cytoplasm and that the rate of nuclear import and export can be modulated by the adherence status of fibroblastic cells.
Journal ArticleDOI
Clinical Care of Two Patients with Ebola Virus Disease in the United States
G. Marshall Lyon,Aneesh K. Mehta,Jay B. Varkey,Kent P. Brantly,Lance Plyler,Anita K. McElroy,Colleen S. Kraft,Jonathan S. Towner,Christina F. Spiropoulou,Ute Ströher,Timothy M. Uyeki,Bruce S. Ribner +11 more
TL;DR: There was a concomitant decline in the amount of virus detected in plasma as the patients' condition improved clinically, and aggressive supportive measures of hydration and electrolyte correction were undertaken.
Journal ArticleDOI
Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination
Ali H. Ellebedy,Katherine J. L. Jackson,Haydn T. Kissick,Helder I. Nakaya,Carl W. Davis,Krishna M. Roskin,Anita K. McElroy,Christine M. Oshansky,Rivka Elbein,Shine Thomas,G. M. Lyon,Christina F. Spiropoulou,Aneesh K. Mehta,Paul G. Thomas,Scott D. Boyd,Rafi Ahmed +15 more
TL;DR: The phenotype and transcriptional program of a subset of antigen-specific B cells, which are called 'activated B cells' (ABCs), that were distinct from ASCs and were committed to the MBC lineage are defined.
Journal ArticleDOI
Human Ebola virus infection results in substantial immune activation
Anita K. McElroy,Rama Akondy,Carl W. Davis,Ali H. Ellebedy,Aneesh K. Mehta,Colleen S. Kraft,G. Marshall Lyon,Bruce S. Ribner,Jay B. Varkey,John Sidney,Alessandro Sette,Shelley Campbell,Ute Ströher,Inger K. Damon,Stuart T. Nichol,Christina F. Spiropoulou,Rafi Ahmed +16 more
TL;DR: Sustained immune activation after the virus was cleared from the plasma is found, observed most strikingly in the persistence of activated CD8 T cells, even 1 mo after the patients’ discharge from the hospital, suggesting continued antigen stimulation after resolution of the disease.