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Author

Anju Chadha

Bio: Anju Chadha is an academic researcher from Indian Institute of Technology Madras. The author has contributed to research in topic(s): Candida parapsilosis & Enantiomeric excess. The author has an hindex of 30, co-authored 135 publication(s) receiving 2800 citation(s). Previous affiliations of Anju Chadha include Indian Institute of Science & National Institutes of Health.


Papers
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Journal ArticleDOI
TL;DR: Important fuel properties of methyl esters of Pongamia oil (Biodiesel) compare well with ASTM and German biodiesel standards.
Abstract: Biodiesel was prepared from the non-edible oil of Pongamia pinnata by transesterification of the crude oil with methanol in the presence of KOH as catalyst. A maximum conversion of 92% (oil to ester) was achieved using a 1:10 molar ratio of oil to methanol at 60 °C. Tetrahydrofuran (THF), when used as a co-solvent increased the conversion to 95%. Solid acid catalysts viz. Hβ-Zeolite, Montmorillonite K-10 and ZnO were also used for this transesterification. Important fuel properties of methyl esters of Pongamia oil (Biodiesel) compare well (Viscosity = 4.8 Cst @ 40 °C and Flash point = 150 °C) with ASTM and German biodiesel standards.

513 citations

Journal ArticleDOI
TL;DR: Enzyme solution-oxidized porous silicon-crystalline silicon structure was used to detect changes in pH during the hydrolysis of tributyrin as a shift in the capacitance-voltage (C-V) characteristics.
Abstract: A novel method for estimating triglycerides is reported. Porous silicon, prepared from p-type (100) crystalline silicon was thermally oxidized and used to immobilise lipase, an enzyme, which hydrolyses triglycerides resulting in the formation of fatty acids. This causes a change in the pH of the solution. Enzyme solution-oxidized porous silicon-crystalline silicon structure was used to detect changes in pH during the hydrolysis of tributyrin as a shift in the capacitance-voltage (C-V) characteristics. Detailed calibration of the sensor is included.

100 citations

Journal ArticleDOI
TL;DR: Both NADH- and NADPH-cytochrome c reductase activities were not significantly changed during the six days of treatment and Oral administration of these two terpenoids did not affect any of the lung-microsomal parameters measured.
Abstract: 1. Metabolites isolated from the urine of rats after oral administration of geraniol (I) were: geranic acid (II), 3-hydroxy-citronellic acid (III), 8-hydroxy-geraniol (IV), 8-carboxy-geraniol (V) and Hildebrandt acid (VI). 2. Metabolites isolated from urine of rats after oral administration of linalool (VII) were 8-hydroxy-linalool (VIII) and 8-carboxy-linalool (IX). 3. After three days of feeding rats with either geraniol or linalool, liver-microsomal cytochrome P-450 was increased. Both NADH- and NADPH-cytochrome c reductase activities were not significantly changed during the six days of treatment. 4. Oral administration of these two terpenoids did not affect any of the lung-microsomal parameters measured.

93 citations

Book ChapterDOI
TL;DR: Although the solution chemistry of diol epoxides is now fairly well understood, a great deal remains to be elucidated regarding their reaction in the presence of DNA, and detailed conformational analysis of adducted DNA should prove to be extremely valuable in developing mechanistic models for the enzymatic processing of chemically altered DNA.
Abstract: Fifteen years ago, we proposed bay-region diol epoxides as the reactive metabolites responsible for the tumorigenic activity of polycyclic aromatic hydrocarbons (Jerina and Daly, 1976; Jerina et al, 1976; Jerina and Lehr, 1977) In the intervening period, extensive studies from several laboratories have provided substantial evidence that over a dozen hydrocarbons are activated by this pathway (Jerina et al, 1984; Lehr et al, 1985; Thakker et al, 1985) Examples have been forthcoming from a variety of structural types including benz- and dibenzanthracenes and acridines, benz- and dibenzpyrenes, chrysenes, and benzo[c]phenanthrene To date, there are no known examples of carcinogenic alternant polycyclic aromatic hydrocarbons for which a bay-region diol epoxide is not an ultimate carcinogen Although a number of mechanistically attractive alternatives to bay-region diol epoxides exist (Watabe et al, 1989; Cavalieri and Rogan, 1985; Miller et al, this volume), the extent of their contribution to the overall carcinogenicity of the hydrocarbons remains to be established

89 citations


Cited by
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01 Jan 2007
Abstract: 介绍了Kirk—Othmer Encyclopedia of Chemical Technology(化工技术百科全书)(第五版)电子图书网络版数据库,并对该数据库使用方法和检索途径作出了说明,且结合实例简单地介绍了该数据库的检索方法。

2,391 citations

Journal ArticleDOI
Abstract: This article is an up-to-date review of the literature available on the subject of liquid biofuels. In search of a suitable fuel alternative to fast depleting fossil fuel and oil reserves and in serious consideration of the environmental issues associated with the extensive use of fuels based on petrochemicals, research work is in progress worldwide. Researchers have been re-directing their interests in biomass based fuels, which currently seem to be the only logical alternative for sustainable development in the context of economical and environmental considerations. Renewable bioresources are available globally in the form of residual agricultural biomass and wastes, which can be transformed into liquid biofuels. However, the process of conversion, or chemical transformation, could be very expensive and not worth-while to use for an economical large-scale commercial supply of biofuels. Hence, there is still need for much research to be done for an effective, economical and efficient conversion process. Therefore, this article is written as a broad overview of the subject, and includes information based on the research conducted globally by scientists according to their local socio-cultural and economic situations.

1,760 citations

Journal ArticleDOI
Abstract: Fossil fuel resources are decreasing daily. Biodiesel fuels are attracting increasing attention worldwide as blending components or direct replacements for diesel fuel in vehicle engines. Biodiesel fuel typically comprises lower alkyl fatty acid (chain length C14–C22), esters of short-chain alcohols, primarily, methanol or ethanol. Various methods have been reported for the production of biodiesel from vegetable oil, such as direct use and blending, microemulsification, pyrolysis, and transesterification. Among these, transesterification is an attractive and widely accepted technique. The purpose of the transesterification process is to lower the viscosity of the oil. The most important variables affecting methyl ester yield during the transesterification reaction are the molar ratio of alcohol to vegetable oil and the reaction temperature. Methanol is the commonly used alcohol in this process, due in part to its low cost. Methyl esters of vegetable oils have several outstanding advantages over other new-renewable and clean engine fuel alternatives. Biodiesel fuel is a renewable substitute fuel for petroleum diesel or petrodiesel fuel made from vegetable or animal fats; it can be used in any mixture with petrodiesel fuel, as it has very similar characteristics, but it has lower exhaust emissions. Biodiesel fuel has better properties than petrodiesel fuel; it is renewable, biodegradable, non-toxic, and essentially free of sulfur and aromatics. Biodiesel seems to be a realistic fuel for future; it has become more attractive recently because of its environmental benefits. Biodiesel is an environmentally friendly fuel that can be used in any diesel engine without modification.

1,639 citations

Journal ArticleDOI
Abstract: Polycyclic aromatic hydrocarbons (PAHs) are formed during incomplete combustion. Domestic wood burning and road traffic are the major sources of PAHs in Sweden. In Stockholm, the sum of 14 different PAHs is 100-200 ng/m(3) at the street-level site, the most abundant being phenanthrene. Benzo[a]pyrene (B[a]P) varies between 1 and 2 ng/m(3). Exposure to PAH-containing substances increases the risk of cancer in humans. The carcinogenicity of PAHs is associated with the complexity of the molecule, i.e., increasing number of benzenoid rings, and with metabolic activation to reactive diol epoxide intermediates and their subsequent covalent binding to critical targets in DNA. B[a]P is the main indicator of carcinogenic PAHs. Fluoranthene is an important volatile PAH because it occurs at high concentrations in ambient air and because it is an experimental carcinogen in certain test systems. Thus, fluoranthene is suggested as a complementary indicator to B[a]P. The most carcinogenic PAH identified, dibenzo[a,l]pyrene, is also suggested as an indicator, although it occurs at very low concentrations. Quantitative cancer risk estimates of PAHs as air pollutants are very uncertain because of the lack of useful, good-quality data. According to the World Health Organization Air Quality Guidelines for Europe, the unit risk is 9 X 10(-5) per ng/m(3) of B[a]P as indicator of the total PAH content, namely, lifetime exposure to 0.1 ng/m(3) would theoretically lead to one extra cancer case in 100,000 exposed individuals. This concentration of 0.1 ng/m(3) of B[a]P is suggested as a health-based guideline. Because the carcinogenic potency of fluoranthene has been estimated to be approximately 20 times less than that of B[a]P, a tentative guideline value of 2 ng/m(3) is suggested for fluoranthene. Other significant PAHs are phenanthrene, methylated phenanthrenes/anthracenes and pyrene (high air concentrations), and large-molecule PAHs such as dibenz[a,h]anthracene, benzo[b]fluoranthene, benzo[k]fluoranthene, and indeno[1,2,3-cd]pyrene (high carcinogenicity). Additional source-specific indicators are benzo[ghi]perylene for gasoline vehicles, retene for wood combustion, and dibenzothiophene and benzonaphthothiophene for sulfur-containing fuels.

1,302 citations

Journal ArticleDOI
Abstract: As the fossil fuels are depleting day by day, there is a need to find out an alternative fuel to fulfill the energy demand of the world. Biodiesel is one of the best available resources that have come to the forefront recently. In this paper, a detailed review has been conducted to highlight different related aspects to biodiesel industry. These aspects include, biodiesel feedstocks, extraction and production methods, properties and qualities of biodiesel, problems and potential solutions of using vegetable oil, advantages and disadvantages of biodiesel, the economical viability and finally the future of biodiesel. The literature reviewed was selective and critical. Highly rated journals in scientific indexes were the preferred choice, although other non-indexed publications, such as Scientific Research and Essays or some internal reports from highly reputed organizations such as International Energy Agency (IEA), Energy Information Administration (EIA) and British Petroleum (BP) have also been cited. Based on the overview presented, it is clear that the search for beneficial biodiesel sources should focus on feedstocks that do not compete with food crops, do not lead to land-clearing and provide greenhouse-gas reductions. These feedstocks include non-edible oils such as Jatropha curcas and Calophyllum inophyllum , and more recently microalgae and genetically engineered plants such as poplar and switchgrass have emerged to be very promising feedstocks for biodiesel production. It has been found that feedstock alone represents more than 75% of the overall biodiesel production cost. Therefore, selecting the best feedstock is vital to ensure low production cost. It has also been found that the continuity in transesterification process is another choice to minimize the production cost. Biodiesel is currently not economically feasible, and more research and technological development are needed. Thus supporting policies are important to promote biodiesel research and make their prices competitive with other conventional sources of energy. Currently, biodiesel can be more effective if used as a complement to other energy sources.

1,262 citations