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Showing papers by "Anju Chadha published in 2008"


Journal ArticleDOI
TL;DR: A highly enantioselective one pot, novel biocatalytic method for the asymmetric reduction of aryl imines with Candida parapsilosis ATCC 7330 in aqueous medium produces the enantiomersically pure R-secondary amines in moderate to good yields with excellent enantiomeric excesses.
Abstract: A highly enantioselective one pot, novel biocatalytic method for the asymmetric reduction of aryl imines is reported. Treatment of aryl imines with Candida parapsilosis ATCC 7330 in aqueous medium produces the enantiomerically pure ( R )-secondary amines in moderate to good yields (55–80%) with excellent enantiomeric excesses (95–>99%).

63 citations


Journal ArticleDOI
TL;DR: In this paper, Pseudomonas cepacia was covalently immobilized on crystalline silicon, porous silicon and silicon nitride surfaces using FTIR (Fourier transform infrared) spectroscopy.

46 citations


Journal ArticleDOI
TL;DR: Biocatalytic deracemisation of racemic allylic alcohols by whole cells of Candida parapsilosis ATCC 7330 resulted in the formation of the (R)-enantiomers in high enantiomeric excesses and isolated yields.
Abstract: Biocatalytic deracemisation of racemic allylic alcohols by whole cells of Candida parapsilosis ATCC 7330 resulted in the formation of the (R)-enantiomers in high enantiomeric excesses (up to >99%) and isolated yields (up to 79%).

42 citations


Journal ArticleDOI
TL;DR: Deracemisation of racemic alkyl 3-(hetero-2-yl)-3-hydroxypropanoates using whole cells of Candida parapsilosis ATCC 7330 resulted in the formation of the ‘ S ’ enantiomer in high enantiomersic excess and isolated yields.
Abstract: Deracemisation of racemic alkyl 3-(hetero-2-yl)-3-hydroxypropanoates using whole cells of Candida parapsilosis ATCC 7330 resulted in the formation of the ‘ S ’ enantiomer in high enantiomeric excess (up to >99% ee) and isolated yields (up to 75%).

18 citations


Journal ArticleDOI
TL;DR: A highly enantioselective one pot, novel biocatalytic method for the asymmetric reduction of aryl imines with Candida parapsilosis ATCC 7330 in aqueous medium produces the enantiomersically pure R-secondary amines in moderate to good yields with excellent enantiomeric excesses.
Abstract: A highly enantioselective one pot, novel biocatalytic method for the asymmetric reduction of aryl imines is reported. Treatment of aryl imines with Candida parapsilosis ATCC 7330 in aqueous medium produces the enantiomerically pure ( R )-secondary amines in moderate to good yields (55–80%) with excellent enantiomeric excesses (95–>99%).

6 citations


Proceedings ArticleDOI
16 Dec 2008
TL;DR: In this article, a composite porous silicon/polysilicon microcantilever for biosensing applications with enhanced sensitivity is reported, which is fabricated by surface micromachining of polysilicon cantilevers followed by the formation of the surface porous layer after release by Reaction Induced Vapor Phase Stain Etch.
Abstract: A novel composite porous silicon/polysilicon microcantilever for biosensing applications with enhanced sensitivity is reported. It is fabricated by surface micromachining of polysilicon cantilevers followed by the formation of the surface porous layer after release by Reaction Induced Vapor Phase Stain Etch. The microcantilevers with porous surface layer are characterized by their morphology that exhibits a dual macro and nanostructure for very effective immobilization of biomolecules. The current work focuses on the fabrication of composite porous silicon/polysilicon microcantilevers, characterization of their morphology and demonstration of improved immobilization of enzymes resulting in enhanced sensing of triglycerides.

6 citations