A
Anju Chadha
Researcher at Indian Institute of Technology Madras
Publications - 140
Citations - 3089
Anju Chadha is an academic researcher from Indian Institute of Technology Madras. The author has contributed to research in topics: Candida parapsilosis & Enantiomeric excess. The author has an hindex of 30, co-authored 135 publications receiving 2800 citations. Previous affiliations of Anju Chadha include Indian Institute of Science & National Institutes of Health.
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Utilization of whole cell mediated deracemization in a chemoenzymatic synthesis of enantiomerically enriched polycyclic chromeno[4,3-b] pyrrolidines
TL;DR: Optically pure propargyl alcohol thus obtained was used as a chiral starting material in the synthesis of enantiomerically enriched poly-substituted pyrrolidines and a pyrrole derivative successfully demonstrating a chemoenzymatic route.
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Regio- and enantio-selective oxidation of diols by Candida parapsilosis ATCC 7330
TL;DR: This is the first report of the regio- and enantio-selective oxidation of diols using C. parapsilosis ATCC 7330, where the secondary alcohol was preferentially oxidized.
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Mechanism of lithium perchlorate/diethyl ether-catalyzed rearrangement of α- and β-endo- and -exo-dicyclopentadienyl vinyl ethers: use of deuterium labeling and a chiral probe
TL;DR: In this paper, the LPDE mediated rearrangement of α- and β-endo-dicyclopentadienyl vinyl ethers resulted in the formation of the aldehyde.
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Pharmacophore based approach to screen and evaluate novel Mycobacterium cell division inhibitors targeting FtsZ – A modelling and experimental study
TL;DR: This studyvirtually screen and shortlist novel compounds from In-house small molecule library as Mtb-FtsZ inhibitors and evaluate their in-vitro and ex-vivo activity, which revealed Piperine, 4-Bromo di-methoxy coumarin, and Di-ethyl amino methyl coumarins as potent MtB-FTSZ GTPase inhibitors which showed considerable antibacterial activity against M. smegmatis.
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Understanding substrate specificity and enantioselectivity of carbonyl reductase from Candida parapsilosis ATCC 7330 (CpCR): Experimental and modeling studies
TL;DR: The optimal orientation required for the high conversion and desired enantioselectivity was analyzed by docking the α/β ketoesters, ketoaldehyde and a ketone with a modeled CpCR.