Anke Ruettger

TL;DR: Comparative genome analysis involving the type strains of currently accepted Chlamydiaceae species and the designated type strains representing the two new clades confirmed that the latter could be classified into two different species as their average nucleotide identity (ANI) values were always below 94%, both with the closest relative species and between themselves.

TL;DR: The combined use of highly specific and sensitive molecular assays facilitated the detection of atypical serovars of C. psittaci, as well as other species of Chlamydia, such as C. pecorum and C. abortus, which raises the question of their epidemiological importance and possible role as pathogens.

TL;DR: This work investigated whether a commercial Micro-ArrayTube could discriminate Chlamydiaceae species in DNA extracted directly from conjunctival samples from 101 trachoma patients in Nepal, and found that 71 (70.3%) villagers were infected.

TL;DR: It is concluded that preparation, storage, homogenization, and quality control are altogether critical steps for in-depth analysis of differential gene expression, especially in hypocellular tissues with highly crosslinked ECM like cartilage.

TL;DR: The assay's validity and suitability for direct typing from tissue and detecting new spoligotypes is shown, and advantages of the microarray methodology include rapidity, ease of operation, automatic data processing, and affordability.