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Ankita Srivastava
Researcher at Motilal Nehru National Institute of Technology Allahabad
Publications - 32
Citations - 1070
Ankita Srivastava is an academic researcher from Motilal Nehru National Institute of Technology Allahabad. The author has contributed to research in topics: Network packet & Computer science. The author has an hindex of 6, co-authored 25 publications receiving 457 citations. Previous affiliations of Ankita Srivastava include ICFAI University, Dehradun & Institute of Chartered Financial Analysts of India.
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Journal ArticleDOI
TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge.
Alicia A. Nugent,Karin Lin,Bettina Van Lengerich,Steve Lianoglou,Laralynne Przybyla,Sonnet S. Davis,Ceyda Llapashtica,Junhua Wang,Do Jin Kim,Dan Xia,Anthony Lucas,Sulochanadevi Baskaran,Patrick C.G. Haddick,Melina Lenser,Timothy K. Earr,Ju Shi,Jason C. Dugas,Benjamin J. Andreone,Todd P. Logan,Hilda Solanoy,Hang Chen,Ankita Srivastava,Suresh Poda,Pascal E. Sanchez,Ryan J. Watts,Thomas Sandmann,Giuseppe Astarita,Joseph W. Lewcock,Kathryn M. Monroe,Gilbert Di Paolo +29 more
TL;DR: Combining chronic demyelination paradigms and cell sorting with RNA sequencing and lipidomics, it is found that wild-type microglia acquire a disease-associated transcriptional state, while TREM2-deficientmicroglia remain largely homeostatic, leading to neuronal damage.
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A review of modern technologies for tackling COVID-19 pandemic.
TL;DR: On-going progress in the modern technology has contributed in improving people's lives and hence there is a solid conviction that validated research plans including artificial intelligence will be of significant advantage in helping people to fight this infection.
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Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys.
Mihalis Kariolis,Robert C. Wells,Jennifer A. Getz,Kwan Wanda,Cathal Mahon,Raymond K. Tong,Do Jin Kim,Ankita Srivastava,Catherine Bedard,Kirk R. Henne,Tina Giese,Victoria A. Assimon,Xiaocheng Chen,Yin Zhang,Hilda Solanoy,Katherine Jenkins,Pascal E. Sanchez,Kane Lesley Ann,Takashi Miyamoto,Kylie S. Chew,Michelle E. Pizzo,Nicholas Liang,Meredith E. K. Calvert,Sarah L. DeVos,Sulochanadevi Baskaran,Sejal S. Hall,Zachary Kevin Sweeney,Robert G. Thorne,Ryan J. Watts,Mark S. Dennis,Adam P. Silverman,Y. Joy Yu Zuchero +31 more
TL;DR: A BBB transport vehicle (TV) comprising an engineered Fc fragment that exploits receptor-mediated transcytosis for CNS delivery of biotherapeutics by binding a highly expressed brain endothelial cell target is described.
Journal ArticleDOI
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice
Ullman Julie,Annie Arguello,Jennifer A. Getz,Akhil Bhalla,Cathal Mahon,Junhua Wang,Tina Giese,Catherine Bedard,Do Jin Kim,Jessica R. Blumenfeld,Nicholas Liang,Ritesh Ravi,Alicia A. Nugent,Sonnet S. Davis,Connie W.Y. Ha,Joseph Duque,Hai L. Tran,Robert C. Wells,Steve Lianoglou,Vinay M. Daryani,Kwan Wanda,Hilda Solanoy,Hoang Nguyen,Timothy K. Earr,Jason C. Dugas,Michael Tuck,Jennifer L. Harvey,Michelle L. Reyzer,Richard M. Caprioli,Sejal S. Hall,Suresh Poda,Pascal E. Sanchez,Mark S. Dennis,Kannan Gunasekaran,Ankita Srivastava,Thomas Sandmann,Kirk R. Henne,Robert G. Thorne,Gilbert Di Paolo,Giuseppe Astarita,Dolores Diaz,Adam P. Silverman,Ryan J. Watts,Zachary Kevin Sweeney,Mihalis Kariolis,Anastasia G. Henry +45 more
TL;DR: Improved brain exposure for ETV fusions containing iduronate 2-sulfatase, the lysosomal enzyme deficient in mucopolysaccharidosis type II, exhibited high intrinsic activity and degraded accumulated substrates in both IDS-deficient cell and in vivo models, highlighting the therapeutic potential of the ETV platform for LSDs.
Journal ArticleDOI
Location based routing protocols in VANET: Issues and existing solutions
TL;DR: This paper analyzes existing VANET routing protocols, critically compares the existing solutions proposed so far, and presents brief description of emerging WAVE+LTE based technology along with some viable direction for future improvement related to location based routing protocols.