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Ann M. Moormann
Researcher at University of Massachusetts Medical School
Publications - 113
Citations - 4334
Ann M. Moormann is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Plasmodium falciparum & Malaria. The author has an hindex of 34, co-authored 94 publications receiving 3747 citations. Previous affiliations of Ann M. Moormann include Case Western Reserve University & Boston Children's Hospital.
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Journal ArticleDOI
Absence of Putative Artemisinin Resistance Mutations Among Plasmodium falciparum in Sub-Saharan Africa: A Molecular Epidemiologic Study
Steve M. Taylor,Steve M. Taylor,Christian M. Parobek,Derrick K. DeConti,Kassoum Kayentao,Sheick Oumar Coulibaly,Brian Greenwood,Harry Tagbor,John V. Williams,Kalifa Bojang,Fanta Njie,Meghna Desai,Simon Kariuki,Julie Gutman,Don P. Mathanga,Andreas Mårtensson,Billy Ngasala,Melissa D. Conrad,Philip J. Rosenthal,Antoinette Tshefu,Ann M. Moormann,John M. Vulule,Ogobara K. Doumbo,Feiko O. ter Kuile,Feiko O. ter Kuile,Steven R. Meshnick,Jeffrey A. Bailey,Jonathan J. Juliano +27 more
TL;DR: An assay to quantify rare polymorphisms in parasite populations that uses a pooled deep-sequencing approach to score allele frequencies is developed and validated by evaluating mixtures of laboratory parasite strains, and used to screen P. falciparum parasites from >1100 African infections collected since 2002.
Journal ArticleDOI
Malaria and pregnancy: placental cytokine expression and its relationship to intrauterine growth retardation.
Ann M. Moormann,Amy D. Sullivan,Rosemary Rochford,Stephen W. Chensue,Paul J. Bock,Thomas Nyirenda,Steven R. Meshnick +6 more
TL;DR: Increased TNF-alpha or IL-8 expression in the placenta was associated with intrauterine growth retardation but not with preterm delivery and the results suggest that malaria infections induce a potentially harmful proinflammatory response in thePlacenta.
Journal ArticleDOI
Exposure to Holoendemic Malaria Results in Elevated Epstein-Barr Virus Loads in Children
Ann M. Moormann,Kiprotich Chelimo,Odada P. Sumba,Mary L. Lutzke,Robert Ploutz-Snyder,Duane W. Newton,James W. Kazura,Rosemary Rochford +7 more
TL;DR: The hypothesis that repeated malaria infections in very young children modulate the persistence of EBV and increase the risk for the development of endemic Burkitt lymphoma is supported.
Journal ArticleDOI
Endemic Burkitt's lymphoma: a polymicrobial disease?
TL;DR: New data suggest how these two pathogens might interact to result in disease and provide insights into the emerging concepts of polymicrobial disease pathogenesis.
Journal ArticleDOI
Differentiation between African populations is evidenced by the diversity of alleles and haplotypes of HLA class I loci
K. Cao,Ann M. Moormann,Kirsten E. Lyke,Carly Masaberg,Odada P. Sumba,Ogobara K. Doumbo,Davy K. Koech,Alex K. Lancaster,Mark P. Nelson,Diogo Meyer,Richard M. Single,Richard M. Single,Robert J. Hartzman,Christopher V. Plowe,James W. Kazura,Dean L. Mann,Marcelo B. Sztein,Glenys Thomson,Marcelo Fernandez-Vina +18 more
TL;DR: The genetic diversity of the HLA system in African populations poses practical challenges for the design of T-cell vaccines and for the transplantation medical community to find HLA-matched unrelated donors for patients in need of an allogeneic transplant.