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Anna Chiara Nascimbeni

Researcher at Paris Descartes University

Publications -  15
Citations -  6045

Anna Chiara Nascimbeni is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Autophagy & Autophagosome. The author has an hindex of 12, co-authored 15 publications receiving 5399 citations. Previous affiliations of Anna Chiara Nascimbeni include University of Paris & French Institute of Health and Medical Research.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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ER–plasma membrane contact sites contribute to autophagosome biogenesis by regulation of local PI3P synthesis

Anna Chiara Nascimbeni, +10 more
- 14 Jul 2017 - 
TL;DR: It is demonstrated that E‐Syts are essential for autophagy‐associated PI3P synthesis at the cortical ER membrane via the recruitment of VMP1, the stabilizing ER partner of the PI3KC3 complex.
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Phosphatidylinositol-3-phosphate in the regulation of autophagy membrane dynamics.

Anna Chiara Nascimbeni, +4 more
- 01 May 2017 - 
TL;DR: The proposed role of PI3P during autophagy is discussed, notably during the autophagosome biogenesis sequence, which was recently confirmed by the demonstration thatPI3P‐binding proteins participate in the complex sequence of signalling that results in autophagous assembly and activity.
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Autophagy Is Required for Memory Formation and Reverses Age-Related Memory Decline.

Mélissa Glatigny, +16 more
- 04 Feb 2019 - 
TL;DR: It is shown that hippocampal autophagy activity is reduced during aging and that restoring its levels is sufficient to reverse age-related memory deficits, and that systemic administration of young plasma into aged mice rejuvenates memory in an Autophagy-dependent manner.
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Autophagy: A Druggable Process.

Etienne Morel, +6 more
- 06 Jan 2017 - 
TL;DR: Each of these levels of regulation of autophagy in mammalian cells is potentially druggable, and, depending on the indication, may be able to stimulate or inhibit autophagosome maturation and lysosomal degradation.