Anna Gerasimova

TL;DR: A new method and the corresponding software tool, PolyPhen-2, which is different from the early tool polyPhen1 in the set of predictive features, alignment pipeline, and the method of classification is presented and performance, as presented by its receiver operating characteristic curves, was consistently superior.

TL;DR: The Deinococcus radiodurans was the first member of this group whose genome was completely sequenced, and a comparative analysis of the two species was performed in this paper.

TL;DR: The results underline the power of a truly unbiased, genome-wide, analysis of CD4 MTB recognition based on the combined use of epitope predictions, high throughput ELISPOT, and T cell libraries using PBMCs from individuals latently infected with MTB.

TL;DR: The results establish the feasibility and utility of enhancer profiling in well-defined populations of specialized cell types involved in disease pathogenesis and identify enhancers with known and potential roles in the normal differentiation of human TH1 cells and TH2 cells.

TL;DR: A modification of the Gibbs sampling motif extraction algorithm, SeSiMCMC (Sequence Similarities by Markov Chain Monte Carlo), which finds structured motifs of these types, as well as non-structured motifs, in a set of unaligned DNA sequences and it is demonstrated that accounting for a symmetric motif structure allows the algorithm to identify weak motifs more accurately.