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Anna Lyra
Researcher at DuPont
Publications - 12
Citations - 613
Anna Lyra is an academic researcher from DuPont. The author has contributed to research in topics: Bifidobacterium animalis & Irritable bowel syndrome. The author has an hindex of 8, co-authored 12 publications receiving 420 citations.
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Journal ArticleDOI
Intestinal microbiota is altered in patients with colon cancer and modified by probiotic intervention
Ashley A. Hibberd,Anna Lyra,Arthur C. Ouwehand,Peter Rolny,Helena Lindegren,Lennart Cedgård,Yvonne Wettergren +6 more
TL;DR: Patients with colon cancer harbour a distinct microbiota signature in the tumour tissue and nearby mucosa, which was altered with probiotic intervention, and results show promise for potential therapeutic benefits in CRC by manipulation of the microbiota.
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Probiotic approach to prevent antibiotic resistance
TL;DR: Concomitant use of probiotics with antibiotics has been observed to reduce the incidence, duration and/or severity of antibiotic-associated diarrhea, which contributes to better adherence to the antibiotic prescription and thereby reduces the evolution of resistance.
Journal ArticleDOI
Irritable bowel syndrome symptom severity improves equally with probiotic and placebo
Anna Lyra,Markku Hillilä,Teppo Huttunen,Sofia Männikkö,Mikko Taalikka,Julia Tennilä,Anneli Tarpila,Sampo J. Lahtinen,Arthur C. Ouwehand,Lea Veijola +9 more
TL;DR: NCFM alleviates moderate to severe abdominal pain, consistent with earlier observations of this strain mitigating visceral pain through increased analgesic receptor expression.
Journal ArticleDOI
Comparison of bacterial quantities in left and right colon biopsies and faeces
Anna Lyra,Sofia D. Forssten,Peter Rolny,Yvonne Wettergren,Sampo J. Lahtinen,Krista Salli,Lennart Cedgård,Elisabeth Odin,Bengt Gustavsson,Arthur C. Ouwehand +9 more
TL;DR: All detected bacteria, except Enterobacteriaceae, were present at higher levels in the faeces than in the mucosa, but the different locations in the colon presented comparable quantities.
Journal ArticleDOI
Nasal microbiota clusters associate with inflammatory response, viral load, and symptom severity in experimental rhinovirus challenge.
Markus J. Lehtinen,Ashley A. Hibberd,Sofia Männikkö,Nicolas Yeung,Tommi Kauko,Sofia D. Forssten,Liisa Lehtoranta,Sampo J. Lahtinen,Buffy Stahl,Anna Lyra,Ronald B. Turner +10 more
TL;DR: The results suggest that nasal microbiota may influence the virus load, host innate immune response, and clinical symptoms during rhinovirus infection, however, further studies are needed.