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Anna Tramontano
Researcher at Sapienza University of Rome
Publications - 200
Citations - 15857
Anna Tramontano is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Protein structure prediction & CASP. The author has an hindex of 61, co-authored 199 publications receiving 14942 citations. Previous affiliations of Anna Tramontano include Istituto Italiano di Tecnologia & Center for Advanced Studies Research and Development in Sardinia.
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Journal ArticleDOI
A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA
Marcella Cesana,Davide Cacchiarelli,Ivano Legnini,Tiziana Santini,Olga Sthandier,Mauro Chinappi,Anna Tramontano,Anna Tramontano,Irene Bozzoni +8 more
TL;DR: It is demonstrated that linc-MD1 exerts the same control over differentiation timing in human myoblasts, and that its levels are strongly reduced in Duchenne muscle cells, indicating that the ceRNA network plays an important role in muscle differentiation.
Journal ArticleDOI
Conformations of immunoglobulin hypervariable regions.
Cyrus Chothia,Cyrus Chothia,Arthur M. Lesk,Anna Tramontano,Michael Levitt,Michael Levitt,Sandra J. Smith-Gill,Gillian M. Air,Steven Sheriff,Steven Sheriff,Eduardo A. Padlan,David R. Davies,W.R. Tulip,Peter M. Colman,Silvia Spinelli,Pedro M. Alzari,Roberto J. Poljak +16 more
TL;DR: There is a small repertoire of main-chain conformations for at least five of the six hypervariable regions of antibodies, and that the particular conformation adopted is determined by a few key conserved residues.
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Critical assessment of methods of protein structure prediction (CASP) — round x
TL;DR: The Critical Assessment of Structure Prediction (CASP) as discussed by the authors was the first attempt to assess the state-of-the-art in protein structure modeling, with a focus on three-dimensional contact information.
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Conformations of the third hypervariable region in the VH domain of immunoglobulins
TL;DR: The general conclusion of this work is that the conformation of H3 shows some regularities, from which rules relating sequence to conformation can be stated, but to a less complete degree than for the other five antigen-binding loops.
Journal ArticleDOI
Critical assessment of methods of protein structure prediction-Round VII.
TL;DR: The state-of-the-art in protein structure prediction was evaluated in the 7th CASP experiment as discussed by the authors, where the authors reported improvements in model accuracy relative to that obtainable from knowledge of a single best template structure.