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Anna Weston
Researcher at ETH Zurich
Publications - 15
Citations - 3536
Anna Weston is an academic researcher from ETH Zurich. The author has contributed to research in topics: Glucocorticoid receptor & Hepatic stellate cell. The author has an hindex of 8, co-authored 15 publications receiving 3229 citations. Previous affiliations of Anna Weston include École Polytechnique Fédérale de Lausanne.
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Journal ArticleDOI
Ecotoxicology of human pharmaceuticals.
TL;DR: It is shown that only very little is known about long-term effects of pharmaceuticals to aquatic organisms, in particular with respect to biological targets, and targeted ecotoxicological studies are needed focusing on subtle environmental effects.
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Long-term effects of early-life environmental manipulations in rodents and primates : Potential animal models in depression research
Christopher R. Pryce,Daniela Rüedi-Bettschen,Andrea C. Dettling,Anna Weston,Holger Russig,Boris Ferger,Joram Feldon +6 more
TL;DR: Some of the evidence-positive and negative-that neglect-like environments in rat pups and monkey infants lead to long-term, depression-like behavioural traits of reduced motivation for reward and impaired coping with adversity, and to altered activity in relevant physiological homeostatic systems are reviewed.
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Early deprivation leads to altered behavioural, autonomic and endocrine responses to environmental challenge in adult Fischer rats
Daniela Rüedi-Bettschen,Wei-Ning Zhang,Holger Russig,Boris Ferger,Anna Weston,Else-Marie Pedersen,Joram Feldon,Christopher R. Pryce +7 more
TL;DR: High sensitivity to an aversive early environment in male Fischer rats therefore constitutes an important model for the study of affective development and its neurobiology.
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Pro-fibrotic compounds induce stellate cell activation, ECM-remodelling and Nrf2 activation in a human 3D-multicellular model of liver fibrosis
TL;DR: For the first time, in vitro recapitulation of key molecular and cellular events leading to liver fibrosis is demonstrated: hepatocellular injury, antioxidant defence response, activation of Kupffer cells and activation of HSC leading to deposition of ECM.
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Postnatal ontogeny of hippocampal expression of the mineralocorticoid and glucocorticoid receptors in the common marmoset monkey.
Christopher R. Pryce,Joram Feldon,Eberhard Fuchs,Irene Knuesel,Thomas Oertle,Christian Sengstag,Marianne Spengler,Elizabeth Weber,Anna Weston,Ana Lúcia Jongen-Rêlo +9 more
TL;DR: Evidence for the postnatal ontogeny of central corticosteroid nuclear receptor expression in a primate is important for understanding both the developmental stage‐specific significance of stress exposure and its potential long‐term effects on health and disease.