A
Anne Stuendl
Researcher at Max Planck Society
Publications - 2
Citations - 445
Anne Stuendl is an academic researcher from Max Planck Society. The author has contributed to research in topics: Endosome & ESCRT. The author has an hindex of 2, co-authored 2 publications receiving 354 citations.
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Journal ArticleDOI
Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson’s disease and dementia with Lewy bodies
Anne Stuendl,Marcel Kunadt,Niels Kruse,Claudia Bartels,Wiebke Moebius,Karin M Danzer,Brit Mollenhauer,Anja Schneider +7 more
TL;DR: CSF exosomes of patients with Parkinson’s disease or dementia with Lewy bodies contain α- synuclein and induce α-synuclein aggregation in a reporter cell line, indicating that exosome support may support inter-neuronal transmission of α- Synuclein pathology.
Journal ArticleDOI
Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation
Marcel Kunadt,Katrin Eckermann,Anne Stuendl,Jing Gong,Jing Gong,Belisa Russo,Belisa Russo,Katrin Strauss,Surya Rai,Sebastian Kügler,Lisandro J. Falomir Lockhart,Martin Schwalbe,Petranka Krumova,Luís M. A. Oliveira,Mathias Bähr,Wiebke Möbius,Johannes Levin,Armin Giese,Niels Kruse,Brit Mollenhauer,Ruth Geiss-Friedlander,Albert C. Ludolph,Axel Freischmidt,Marisa S. Feiler,Karin M Danzer,Markus Zweckstetter,Markus Zweckstetter,Thomas M. Jovin,Mikael Simons,Jochen H. Weishaupt,Anja Schneider +30 more
TL;DR: The study reveals a function of SUMO protein modification as a Ubiquitin-independent ESCRT sorting signal, regulating the extracellular vesicle release of α-Synuclein, and proposes that sumo-dependent sorting constitutes a mechanism with more general implications for cell biology.