Anne Vral

TL;DR: The best model, which included exposure to genotoxic factors, host factors, methods, and scoring criteria, explained 75% of the total variance, with the largest contribution attributable to laboratory methods.

TL;DR: In this article, established and emerging dosimetry methods are reviewed, which can be used immediately and retrospectively following external ionising radiation exposure, and individual characteristics of these techniques, their limitations and potential for further development are discussed, and their usefulness in specific exposure scenarios is discussed.

TL;DR: Biological dosimetry, based on the analysis ofmicronuclei (MN) in the cytokinesis-block micronucleus (CBMN) assay can be used as an alternative method for scoring dicentric chromosomes in the field of radiation protection.

TL;DR: The APE1 Asp148Glu polymorphism is highly predictive for lung cancer, and cumulative cigarette smoking modifies the associations between the XRCC1 Arg399Gln and the XPD Lys751Gln polymorphisms and lung cancer risk.

TL;DR: In this article, an inter-laboratory slide-scoring exercise was performed among 34 laboratories from 21 countries with a total of 51 slide scorers involved, and the results of these studies indicate clearly that even after standardizing culture and scoring conditions it will be necessary to calibrate scorers and laboratories if MN, MNed cell and nucleoplasmic bridge frequencies are reliably compared among laboratories and among populations.