Annemart Koornneef

TL;DR: Analysis of the Arabidopsis mutant npr1 revealed that the antagonistic effect of SA on JA signaling requires the regulatory protein NPR1, indicating that cross-talk between SA and JA is modulated through a novel function of NPR1 in the cytosol.

TL;DR: Plants are equipped with an array of defense mechanisms to protect themselves against attack by herbivorous insects and microbial pathogens, some of which are preexisting, whereas others are only activated upon insect or pathogen invasion.

TL;DR: It is demonstrated that suppression of the JA pathway by SA functions downstream of the E3 ubiquitin-ligase Skip-Cullin-F-box complex SCFCOI1, which targets JASMONATE ZIM-domain transcriptional repressor proteins (JAZs) for proteasome-mediated degradation.

TL;DR: Pharmacological experiments revealed that transcription of JA-responsive marker genes, such as PDF1.2 and VSP2, is highly sensitive to suppression by SA, and SA-mediated redox modulation plays an important role in the SA- mediated attenuation of the JA signaling pathway.

TL;DR: Pharmacological experiments showed that ET acts synergistically on SA-induced PR-1, suggesting that the increased production of ET upon herbivore feeding sensitizes the tissue to respond faster to SA, thereby contributing to an enhanced defensive capacity toward pathogens, such as TCV, that trigger SA-dependent defenses upon infection.