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Anthony Holtmaat
Researcher at University of Geneva
Publications - 71
Citations - 9238
Anthony Holtmaat is an academic researcher from University of Geneva. The author has contributed to research in topics: Dendritic spine & Somatosensory system. The author has an hindex of 35, co-authored 69 publications receiving 8142 citations. Previous affiliations of Anthony Holtmaat include Howard Hughes Medical Institute.
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Journal ArticleDOI
Experience-dependent structural synaptic plasticity in the mammalian brain.
Anthony Holtmaat,Karel Svoboda +1 more
TL;DR: Recent evidence for structural forms of synaptic plasticity in the mammalian cortex involves cell type-specific structural plasticity: some boutons and dendritic spines appear and disappear, accompanied by synapse formation and elimination, respectively.
Journal ArticleDOI
Transient and Persistent Dendritic Spines in the Neocortex In Vivo
Anthony Holtmaat,Joshua T. Trachtenberg,Linda Wilbrecht,Gordon M. Shepherd,Xiaoqun Zhang,Graham Knott,Karel Svoboda +6 more
TL;DR: In 6-month-old mice, spines turn over more slowly in visual compared to somatosensory cortex, possibly reflecting differences in the capacity for experience-dependent plasticity in these brain regions.
Journal ArticleDOI
Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window
Anthony Holtmaat,Anthony Holtmaat,Tobias Bonhoeffer,David K. Chow,JA Chuckowree,Vincenzo De Paola,Vincenzo De Paola,Sonja B. Hofer,Sonja B. Hofer,Mark Hübener,Tara Keck,Graham Knott,Graham Knott,Wei-Chung Allen Lee,Ricardo Mostany,Thomas D. Mrsic-Flogel,Thomas D. Mrsic-Flogel,Elly Nedivi,Carlos Portera-Cailliau,Karel Svoboda,Karel Svoboda,Joshua T. Trachtenberg,Linda Wilbrecht,Linda Wilbrecht +23 more
TL;DR: A chronic cranial window is described to obtain optical access to the mouse cerebral cortex for long-term imaging and the entire dendritic and axonal arbor of individual neurons can be reconstructed.
Journal ArticleDOI
Experience-dependent and cell-type-specific spine growth in the neocortex.
TL;DR: The data indicate that novel sensory experience drives the stabilization of new spines on subclasses of cortical neurons, which probably underlie experience-dependent remodelling of specific neocortical circuits.
Journal ArticleDOI
Spine growth precedes synapse formation in the adult neocortex in vivo.
TL;DR: The data show that spine growth precedes synapse formation and that new synapses form preferentially onto existing boutons, and in some instances, two new spines contacted the same axon.