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Anthony Wynshaw-Boris
Researcher at Case Western Reserve University
Publications - 256
Citations - 39396
Anthony Wynshaw-Boris is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Gene & Wnt signaling pathway. The author has an hindex of 96, co-authored 250 publications receiving 37510 citations. Previous affiliations of Anthony Wynshaw-Boris include Howard Hughes Medical Institute & Salk Institute for Biological Studies.
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Journal ArticleDOI
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs
Yasushi Okazaki,Masaaki Furuno,Takeya Kasukawa,Jun Adachi,Hidemasa Bono,S. Kondo,Itoshi Nikaido,Naoki Osato,Rintaro Saito,Harukazu Suzuki,Itaru Yamanaka,H. Kiyosawa,Ken Yagi,Yasuhiro Tomaru,Yuki Hasegawa,A. Nogami,Christian Schönbach,Takashi Gojobori,Richard M. Baldarelli,David P. Hill,Carol J. Bult,David A. Hume,John Quackenbush,Lynn M. Schriml,Alexander Kanapin,Hideo Matsuda,Serge Batalov,Kirk W. Beisel,Judith A. Blake,Dirck W. Bradt,Vladimir Brusic,Cyrus Chothia,Lori E. Corbani,S. Cousins,Emiliano Dalla,Tommaso A. Dragani,Colin F. Fletcher,Colin F. Fletcher,Alistair R. R. Forrest,K. S. Frazer,Terry Gaasterland,Manuela Gariboldi,Carmela Gissi,Adam Godzik,Julian Gough,Sean M. Grimmond,Stefano Gustincich,Nobutaka Hirokawa,Ian J. Jackson,Erich D. Jarvis,Akio Kanai,Hideya Kawaji,Hideya Kawaji,Yuka Imamura Kawasawa,Rafal M. Kedzierski,Benjamin L. King,Akihiko Konagaya,Igor V. Kurochkin,Yong-Hwan Lee,Boris Lenhard,Paul A. Lyons,Donna Maglott,Lois J. Maltais,Luigi Marchionni,Louise M. McKenzie,Harukata Miki,Takeshi Nagashima,Koji Numata,Toshihisa Okido,William J. Pavan,Geo Pertea,Graziano Pesole,Nikolai Petrovsky,Ramesh S. Pillai,Joan Pontius,D. Qi,Sridhar Ramachandran,Timothy Ravasi,Jonathan C. Reed,Deborah J Reed,Jeffrey G. Reid,Brian Z. Ring,M. Ringwald,Albin Sandelin,Claudio Schneider,Colin A. Semple,Mitsutoshi Setou,K. Shimada,Razvan Sultana,Yoichi Takenaka,Martin S. Taylor,Rohan D. Teasdale,Masaru Tomita,Roberto Verardo,Lukas Wagner,Claes Wahlestedt,Y. Wang,Yoshiki Watanabe,Christine A. Wells,Laurens G. Wilming,Anthony Wynshaw-Boris,Masashi Yanagisawa,Ivana V. Yang,L. Yang,Zheng Yuan,Mihaela Zavolan,Yunhui Zhu,Anne M. Zimmer,Piero Carninci,N. Hayatsu,Tomoko Hirozane-Kishikawa,Hideaki Konno,M. Nakamura,Naoko Sakazume,K. Sato,Toshiyuki Shiraki,Kazunori Waki,Jun Kawai,Katsunori Aizawa,Takahiro Arakawa,S. Fukuda,A. Hara,W. Hashizume,K. Imotani,Y. Ishii,Masayoshi Itoh,Ikuko Kagawa,A. Miyazaki,K. Sakai,D. Sasaki,K. Shibata,Akira Shinagawa,Ayako Yasunishi,Masayasu Yoshino,Robert H. Waterston,Eric S. Lander,Jane Rogers,Ewan Birney,Yoshihide Hayashizaki +138 more
TL;DR: The present work, completely supported by physical clones, provides the most comprehensive survey of a mammalian transcriptome so far, and is a valuable resource for functional genomics.
Journal ArticleDOI
IKK-beta links inflammation to obesity-induced insulin resistance.
Melek C. Arkan,Andrea L. Hevener,Florian R. Greten,Shin Maeda,Zhi-Wei Li,Jeffrey M. Long,Anthony Wynshaw-Boris,Giuseppe Poli,Jerrold M. Olefsky,Michael Karin +9 more
TL;DR: The importance of liver cell IKK-β in hepatic insulin resistance and the central role of myeloid cells in development of systemic insulin resistance are demonstrated and it is suggested that inhibition of Ikk-β, especially in myeloids cells, may be used to treat insulin resistance.
Journal ArticleDOI
Atm-deficient mice: a paradigm of ataxia telangiectasia.
Carrolee Barlow,Shinji Hirotsune,Richard Paylor,Marek Liyanage,Michael Eckhaus,Francis J Collins,Yosef Shiloh,Jacqueline N. Crawley,Thomas Ried,Danilo A. Tagle,Anthony Wynshaw-Boris +10 more
TL;DR: Atm-disrupted mice recapitulate the ataxia telangiectasia phenotype in humans, providing a mammalian model in which to study the pathophysiology of this pleiotropic disorder.
Journal ArticleDOI
Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies.
Jacqueline N. Crawley,John K. Belknap,Allan C. Collins,John C. Crabbe,Wayne N. Frankel,Norman D. Henderson,Robert Hitzemann,Stephen C. Maxson,Lucinda L. Miner,Alcino J. Silva,Jeanne M. Wehner,Anthony Wynshaw-Boris,Richard Paylor +12 more
TL;DR: Strain distributions are described for open field activity, learning and memory tasks, aggression, sexual and parental behaviors, acoustic startle and prepulse inhibition, and the behavioral actions of ethanol, nicotine, cocaine, opiates, antipsychotics, and anxiolytics.
Journal ArticleDOI
Stat5a is mandatory for adult mammary gland development and lactogenesis.
Xiuwen Liu,Gertraud W. Robinson,Kay Uwe Wagner,Lisa Garrett,Anthony Wynshaw-Boris,Lothar Hennighausen +5 more
TL;DR: It is document that Stat5a is the principal and an obligate mediator of mammopoietic and lactogenic signaling.