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Antonio Díaz-López
Researcher at University of Texas MD Anderson Cancer Center
Publications - 26
Citations - 910
Antonio Díaz-López is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: International Prognostic Index & Cancer. The author has an hindex of 15, co-authored 23 publications receiving 789 citations. Previous affiliations of Antonio Díaz-López include Complutense University of Madrid & Spanish National Research Council.
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Journal ArticleDOI
Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives
TL;DR: Understanding the regulation of EMT by miRNAs opens new avenues for the diagnosis and prognosis of tumors and identifies potential therapeutic targets that might help to negatively impact on metastasis dissemination and increasing patient survival.
Journal ArticleDOI
Correlations of telomere length, telomerase activity, and telomeric‐repeat binding factor 1 expression in colorectal carcinoma
Cristina García-Aranda,Carmen de Juan,Antonio Díaz-López,Andrés Sánchez-Pernaute,A.J. Torres,Eduardo Díaz-Rubio,J.L. Balibrea,Manuel Benito,Pilar Iniesta +8 more
TL;DR: The objectives of the current study were to investigate the mechanisms implicated in telomere length in colorectal carcinoma and to evaluate the prognostic impact of telomeres status.
Journal ArticleDOI
Molecular profiling of circulating tumor cells links plasticity to the metastatic process in endometrial cancer
Lorena Alonso-Alconada,Laura Muinelo-Romay,Kadri Madissoo,Antonio Díaz-López,Camilla Krakstad,Jone Trovik,Elisabeth Wik,Dharani K. Hapangama,Lieve Coenegrachts,Amparo Cano,Antonio Gil-Moreno,Luis Chiva,Juan Cueva,Maria Vieito,Eugenia Ortega,Javier Mariscal,Eva Colas,Josep Castellví,M. Cusido,Xavier Dolcet,Hans W. Nijman,Tjalling Bosse,John Green,Andrea Romano,Jaume Reventós,Rafael López-López,Helga B. Salvesen,Frédéric Amant,Xavier Matias-Guiu,Gema Moreno-Bueno,Gema Moreno-Bueno,Miguel Abal +31 more
TL;DR: In this paper, the presence and phenotypic features of Circulating Tumor Cells (CTC) in high-risk endometrial cancer patients were investigated in the framework of the European Network for Individualized Treatment in EC (ENITEC), and the results indicated a remarkable plasticity phenotype defined by the expression of the EMT markers ETV5, NOTCH1, SNAI1, TGFB1, ZEB1 and ZEB2.
Journal ArticleDOI
A core microRNA signature associated with inducers of the epithelial-to-mesenchymal transition.
Juan Díaz-Martín,Antonio Díaz-López,Gema Moreno-Bueno,M Ángeles Castilla,Juan Manuel Rosa-Rosa,Amparo Cano,José Palacios,José Palacios +7 more
TL;DR: A core subset of deregulated miRNAs were identified that were further validated in vivo, studying endometrial carcinosarcoma (ECS), a tumour entity that represents an extreme example of phenotypic plasticity.
Journal ArticleDOI
Biological and clinical significance of MMP-2, MMP-9, TIMP-1 and TIMP-2 in non-small cell lung cancer.
Pilar Iniesta,Alberto Morán,Carmen de Juan,Ana Gómez,Florentino Hernando,Cristina García-Aranda,Cristina Frías,Antonio Díaz-López,Francisco-Javier Rodríguez-Jiménez,J.L. Balibrea,Manuel Benito +10 more
TL;DR: It is concluded that MMP-9 and TIMP-1 levels of synthesis could be useful for the selection of patients with potentially unfavourable clinical evolution in order to establish adjuvant therapy protocols.