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Anup Madan

Researcher at Institute for Systems Biology

Publications -  36
Citations -  32705

Anup Madan is an academic researcher from Institute for Systems Biology. The author has contributed to research in topics: DNA methylation & Genome. The author has an hindex of 24, co-authored 33 publications receiving 30899 citations. Previous affiliations of Anup Madan include University of Iowa.

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Journal ArticleDOI

Initial sequencing and analysis of the human genome.

Eric S. Lander, +248 more
- 15 Feb 2001 - 
TL;DR: The results of an international collaboration to produce and make freely available a draft sequence of the human genome are reported and an initial analysis is presented, describing some of the insights that can be gleaned from the sequence.
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CAP3: A DNA Sequence Assembly Program

TL;DR: The third generation of the CAP sequence assembly program is described, which has a capability to clip 5' and 3' low-quality regions of reads and uses forward-reverse constraints to correct assembly errors and link contigs.
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Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.

Robert L. Strausberg, +81 more
TL;DR: The National Institutes of Health Mammalian Gene Collection (MGC) Program is a multiinstitutional effort to identify and sequence a cDNA clone containing a complete ORF for each human and mouse gene.
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The status, quality, and expansion of the NIH full-length cDNA project: The Mammalian Gene Collection (MGC)

Daniela S. Gerhard, +118 more
- 01 Oct 2004 - 
TL;DR: Comparison of the sequence of the MGC clones to reference genome sequences reveals that most cDNA clones are of very high sequence quality, although it is likely that some cDNAs may carry missense variants as a consequence of experimental artifact, such as PCR, cloning, or reverse transcriptase errors.
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The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies

TL;DR: It is concluded that both genetic variation and epigenetic modifications contribute to the regulation of SLC6A4 function and that more in‐depth studies of the molecular mechanisms controlling gene activity and the relationship of these mechanisms to behavioral illness are indicated.