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Apilak Worachartcheewan
Researcher at Mahidol University
Publications - 80
Citations - 1906
Apilak Worachartcheewan is an academic researcher from Mahidol University. The author has contributed to research in topics: Quantitative structure–activity relationship & Molecular descriptor. The author has an hindex of 22, co-authored 75 publications receiving 1599 citations.
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Journal ArticleDOI
Bioactive Metabolites from Spilanthes acmella Murr.
Supaluk Prachayasittikul,Saowapa Suphapong,Apilak Worachartcheewan,Ratana Lawung,Somsak Ruchirawat,Virapong Prachayasittikul +5 more
TL;DR: These findings demonstrate for the first time the potential benefits of this medicinal plant as a rich source of high therapeutic value compounds for medicines, cosmetics, supplements and as a health food.
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Antimicrobial and antioxidative activities of bioactive constituents from Hydnophytum formicarum Jack.
Supaluk Prachayasittikul,Prasit Buraparuangsang,Apilak Worachartcheewan,Chartchalerm Isarankura-Na-Ayudhya,Somsak Ruchirawat,Virapong Prachayasittikul +5 more
TL;DR: The results show that the crude hexane, dichloromethane, ethyl acetate and methanol extracts exert antimicrobial and antioxidative activities and propose that Hydnophytum formicarum Jack.
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Roles of Pyridine and Pyrimidine Derivatives as Privileged Scaffolds in Anticancer Agents.
Supaluk Prachayasittikul,Ratchanok Pingaew,Apilak Worachartcheewan,Nujarin Sinthupoom,Veda Prachayasittikul,Somsak Ruchirawat,Virapong Prachayasittikul +6 more
TL;DR: Pyridine- and pyrimidine-based anticancer drugs have been developed based on structural modification of these core structures based on substitution with moieties and rings, conjugation with other compounds, and coordination with metal ions.
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Synthesis, anticancer activity and QSAR study of 1,4-naphthoquinone derivatives
Veda Prachayasittikul,Ratchanok Pingaew,Apilak Worachartcheewan,Chanin Nantasenamat,Supaluk Prachayasittikul,Somsak Ruchirawat,Virapong Prachayasittikul +6 more
TL;DR: Quantitative structure-activity relationship (QSAR) investigations provided good predictive performance and could provide guidelines for further development of novel and potent anticancer agents.
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Novel 1,4-naphthoquinone-based sulfonamides: Synthesis, QSAR, anticancer and antimalarial studies.
Ratchanok Pingaew,Veda Prachayasittikul,Apilak Worachartcheewan,Chanin Nantasenamat,Supaluk Prachayasittikul,Somsak Ruchirawat,Somsak Ruchirawat,Virapong Prachayasittikul +7 more
TL;DR: A novel series of 1,4-naphthoquinones tethered by open and closed chain sulfonamide moieties showed a broad spectrum of cytotoxic activities against all of the tested cancer cell lines including HuCCA-1, HepG2, A549 and MOLT-3 and was suggested for further development as anticancer and antimalarial agents.