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Arnaud Marchant
Researcher at Université libre de Bruxelles
Publications - 200
Citations - 12710
Arnaud Marchant is an academic researcher from Université libre de Bruxelles. The author has contributed to research in topics: Vaccination & Antibody. The author has an hindex of 54, co-authored 180 publications receiving 11016 citations. Previous affiliations of Arnaud Marchant include University of Cambridge & Free University of Brussels.
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Journal ArticleDOI
Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia.
C Gérard,Catherine Bruyns,Arnaud Marchant,Daniel Abramowicz,Peter Vandenabeele,Anne Delvaux,Walter Fiers,Michel Goldman,Thierry Velu +8 more
TL;DR: It is concluded that IL-10 inhibits in vivo TNF secretion and protects against the lethality of endotoxin in a murine model of septic shock.
Journal ArticleDOI
Immune Activation and CD8+ T-Cell Differentiation towards Senescence in HIV-1 Infection
Laura Papagno,Celsa A. Spina,Arnaud Marchant,Mariolina Salio,Nathalie Rufer,Susan J. Little,Tao Dong,G Chesney,Anele Waters,Philippa Easterbrook,P R Dunbar,Dawn Shepherd,Vincenzo Cerundolo,Vincent C. Emery,Paul D. Griffiths,Christopher P. Conlon,Andrew J. McMichael,Douglas D. Richman,Sarah Rowland-Jones,Victor Appay +19 more
TL;DR: It is shown that the activation level and the differentiation state of T-cells are closely related and may be part of the mechanism through which HIV-1-mediated immune activation exhausts the capacity of the immune system.
Journal ArticleDOI
Interleukin-10 inhibits B7 and intercellular adhesion molecule-1 expression on human monocytes
Fabienne Willems,Arnaud Marchant,Jean Pierre Delville,Catherine Gerard,Anne Delvaux,Thierry Velu,Mark de Boer,Michel Goldman +7 more
TL;DR: The ability of IL‐10 to decrease both ICAM‐1 and B7 expression on monocytes might contribute to its immunosuppressive properties.
Journal Article
Newborns Develop a Th1-Type Immune Response to Mycobacterium bovis Bacillus Calmette-Guérin Vaccination
Arnaud Marchant,Tessa Goetghebuer,Martin O. C. Ota,Ingrid Wolfe,Serign J. Ceesay,Donat De Groote,Tumani Corrah,Steve Bennett,J. G. Wheeler,Kris Huygen,Peter Aaby,Keith P. W. J. McAdam,Melanie J. Newport +12 more
TL;DR: It is found that BCG vaccination at birth induces a memory Th1-type response of similar magnitude to that when given later in life.
Journal ArticleDOI
Immunological mechanisms of vaccine-induced protection against COVID-19 in humans.
TL;DR: Most COVID-19 vaccines have been designed to elicit immune responses, ideally neutralizing antibodies (NAbs), against the SARS-CoV-2 spike protein this article.