A
Arsalan Kharazmi
Researcher at University of Copenhagen
Publications - 147
Citations - 7976
Arsalan Kharazmi is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Antigen & Peripheral blood mononuclear cell. The author has an hindex of 52, co-authored 147 publications receiving 7676 citations. Previous affiliations of Arsalan Kharazmi include Copenhagen University Hospital.
Papers
More filters
Journal ArticleDOI
Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung.
Kalai Mathee,Oana Ciofu,Claus Sternberg,Peter W. Lindum,Joan I. A. Campbell,Per Anker Jensen,Anders H. Johnsen,Michael Givskov,Dennis E. Ohman,Molin Søren,Niels Høiby,Arsalan Kharazmi +11 more
TL;DR: The mucoid phenotype among the strains infecting CF patients indicates overproduction of a linear polysaccharide called alginate, which suggests that gene activation in bacteria by toxic oxygen radicals, similar to that found in plants and mammalian cells, may serve as a defence mechanism for the bacteria.
Journal ArticleDOI
Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth.
TL;DR: The biofilm mode of growth is the survival strategy of environmental bacteria like Pseudomonas aeruginosa, which occurs in the lungs of chronically infected cystic fibrosis patients, where they protect the bacteria against antibiotics and the immune response.
Journal ArticleDOI
Inhibition of Fumarate Reductase in Leishmania major and L. donovani by Chalcones
TL;DR: Findings indicate that FRD, one of the enzymes of the parasite respiratory chain, might be the specific target for the chalcones tested, and could be an excellent target for antiprotozoal drugs.
Journal ArticleDOI
An Antiinflammatory Galactolipid from Rose Hip (Rosa canina) that Inhibits Chemotaxis of Human Peripheral Blood Neutrophils in Vitro
TL;DR: The galactolipid (2S)-1,2-di-O-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]-3-O-beta-d-galactopyranosyl glycerol isolated from dried and milled fruits of Rosa canina is an antiinflammatory agent with inhibitory effects on chemotaxis of human peripheral blood neutrophils in vitro.
Journal ArticleDOI
Human polymorphonuclear leukocyte response to Pseudomonas aeruginosa grown in biofilms.
TL;DR: The interaction of human neutrophils with Pseudomonas aeruginosa biofilms was examined by using a chemiluminescence assay and the reduced response to P. aerug inosa biofilm could play a role in the persistence of bacteria in chronic infections.