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Arthur Kaser

Researcher at University of Cambridge

Publications -  209
Citations -  22542

Arthur Kaser is an academic researcher from University of Cambridge. The author has contributed to research in topics: Inflammatory bowel disease & Unfolded protein response. The author has an hindex of 66, co-authored 194 publications receiving 19375 citations. Previous affiliations of Arthur Kaser include Innsbruck Medical University & Brigham and Women's Hospital.

Papers
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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

Arthur Kaser, +10 more
- 05 Sep 2008 - 
TL;DR: It is reported that XBP1 deletion in intestinal epithelial cells (IECs) results in spontaneous enteritis and increased susceptibility to induced colitis secondary to both Paneth cell dysfunction and an epithelium that is overly reactive to inducers of IBD such as bacterial products (flagellin) and TNFalpha.
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Visfatin, an adipocytokine with proinflammatory and immunomodulating properties.

Alexander R. Moschen, +6 more
- 01 Feb 2007 - 
TL;DR: It is shown that recombinant visfatin activates human leukocytes and induces cytokine production and in vivo, visFatin induces circulating IL-6 in BALB/c mice and can be considered a new proinflammatory adipocytokine.
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Gut microbiome, obesity, and metabolic dysfunction.

Herbert Tilg, +1 more
- 01 Jun 2011 - 
TL;DR: The prevalence of obesity and related disorders such as metabolic syndrome has vastly increased throughout the world, and dietary composition and caloric intake appear to swiftly regulate intestinal microbial composition and function.
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Paneth cells as a site of origin for intestinal inflammation

Timon E. Adolph, +27 more
- 14 Nov 2013 - 
TL;DR: Genetically and environmentally controlled UPR function within Paneth cells may set the threshold for the development of intestinal inflammation upon hypomorphic ATG16L1 function and implicate ileal Crohn’s disease as a specific disorder ofPaneth cells.