BIOE 402. Medical Technology Assessment. 2 or 3 hours. Bioentrepreneur course. Assessment of medical technology in the context of commercialization. Objectives, competition, market share, funding, pricing, manufacturing, growth, and intellectual property; many issues unique to biomedical products. Course Information: 2 undergraduate hours. 3 graduate hours. Prerequisite(s): Junior standing or above and consent of the instructor.

“Bioinformatics” 특집을 내면서

Agency for International Development.

Tetraodon nigroviridis is a freshwater puffer fish with the smallest known vertebrate genome. Here, we report a draft genome sequence with long-range linkage and substantial anchoring to the 21 Tetraodon chromosomes. Genome analysis provides a greatly improved fish gene catalogue, including identifying key genes previously thought to be absent in fish. Comparison with other vertebrates and a urochordate indicates that fish proteins have diverged markedly faster than their mammalian homologues. Comparison with the human genome suggests ∼900 previously unannotated human genes. Analysis of the Tetraodon and human genomes shows that whole-genome duplication occurred in the teleost fish lineage, subsequent to its divergence from mammals. The analysis also makes it possible to infer the basic structure of the ancestral bony vertebrate genome, which was composed of 12 chromosomes, and to reconstruct much of the evolutionary history of ancient and recent chromosome rearrangements leading to the modern human karyotype.

/pdf/genome-duplication-in-the-teleost-fish-tetraodon-qw9iuo5jxx.pdf

Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype

Neurospora crassa is a central organism in the history of twentieth-century genetics, biochemistry and molecular biology. Here, we
report a high-quality draft sequence of the N. crassa genome. The approximately 40-megabase genome encodes about 10,000
protein-coding genes—more than twice as many as in the fission yeast Schizosaccharomyces pombe and only about 25% fewer
than in the fruitfly Drosophila melanogaster. Analysis of the gene set yields insights into unexpected aspects of Neurospora biology
including the identification of genes potentially associated with red light photobiology, genes implicated in secondary metabolism,
and important differences in Ca21 signalling as compared with plants and animals. Neurospora possesses the widest array of
genome defence mechanisms known for any eukaryotic organism, including a process unique to fungi called repeat-induced
point mutation (RIP). Genome analysis suggests that RIP has had a profound impact on genome evolution, greatly slowing the
creation of new genes through genomic duplication and resulting in a genome with an unusually low proportion of closely related
genes.

/pdf/the-genome-sequence-of-the-filamentous-fungus-neurospora-2jw3s2832k.pdf

The genome sequence of the filamentous fungus Neurospora crassa

Outline of the classification of flowering plants (Magnoliophyta)

Chromosome techniques: Theory and practice

RIASSUNTOL'A delinea l'importanza delle modificazioni cromosomiche del soma nel problema della speciazione delle piante che si riproducono vegetativamente

https://www.tandfonline.com/doi/pdf/10.1080/00087114.1956.10797584

A New Concept of a Means of Speciation in Plants

Myconanotechnology is an emerging field, where fungi can be harnessed for the synthesis of nanomaterials or nanostructures with desirable shape and size. Though myconanotechnology is in its infancy, potential applications provide exciting waves of transformation in agriculture and fascinate microbiologists and other researchers to contribute in providing incremental solutions through green chemistry approaches for advancing food security. In this article, we provide a brief overview of the research efforts on the mycogenic synthesis of nanoparticles with particular emphasis on mechanisms and potential applications in agriculture and allied sectors.

http://microbiology.ukzn.ac.za/Libraries/MICR712/Myconanotechnology.sflb.ashx?download=true

Arun Kumar Sharma

Papers

Chromosome techniques: Theory and practice

A New Concept of a Means of Speciation in Plants

Myconanotechnology in agriculture: a perspective

Chromosomes in evolution of eukaryotic groups

Plant genome : biodiversity and evolution