Asa C. Black

TL;DR: This study details the profile of 13 cell surface cluster differentiation markers on human reserve stem cells derived from connective tissues as well as lineage‐uncommitted pluripotent stem cells capable of forming muscle, adipocytes, cartilage, bone, fibroblasts, and endothelial cells.

TL;DR: The results suggest that progenitor mesenchymal stem cells and putative pluripotent mesenchyl stem cells with the potential to form at least four tissues of mesodermal origin have a widespread distribution throughout the body, being located within the connective tissue compartments of many organs and organ systems.

TL;DR: Until recently it was generally assumed that the precursor cells in postnatal individuals were limited to lineage-committed progenitor cells specific for various tissues, but studies by Young, his colleagues, and others have demonstrated the presence of two categories of precursor cells that reside within the organs and tissues of postnatal animals.

TL;DR: This study examined human pluripotent and progenitor cells isolated from fetal, mature, and geriatric individuals for the possible presence of 15 CD markers, and reports the first identification of CD10, CD13, CD56, and MHC Class-I cell surface antigens on these human cells.

TL;DR: The authors propose that the activation of quiescent tissue-specific progenitor cells, germ-layer lineage stem cells, and/or pluripotent stem cells may be a potential explanation, along with dedifferentiation and transdifferentiation, for the process of tissue restoration.