Atsuo Amano

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: It is shown that autophagosomes form at the ER–mitochondria contact site in mammalian cells, and new insight is provided into organelle biogenesis by demonstrating that the ER-resident SNARE protein syntaxin 17 (STX17) binds ATG14 and recruits it to the ER—mitochondia contact site.

TL;DR: It is found that the autophagic machinery could effectively eliminate pathogenic group A Streptococcus within nonphagocytic cells within autophagy-deficient Atg5–/– cells.

TL;DR: The fimbria variations may have an influence on the development of periodontal disease as shown in the relationship between clonal variation of fimbriae and bacterial pathogenicity of various strains.