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Attilio Naccarato

Other affiliations: University of Waterloo
Bio: Attilio Naccarato is an academic researcher from University of Calabria. The author has contributed to research in topics: Solid-phase microextraction & Selected reaction monitoring. The author has an hindex of 22, co-authored 45 publications receiving 1091 citations. Previous affiliations of Attilio Naccarato include University of Waterloo.


Papers
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TL;DR: The work aims at developing a simple and rapid method for the quantification of dopamine, serotonin and norepinephrine in human urine by using the use of solid phase microextraction combined with gas chromatography-triple quadrupole mass spectrometry (GC-QqQ-MS) system and a central composite design (CCD) was applied.

105 citations

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TL;DR: The origin of tomato fruits and the areas of production as "Italy" and "non-Italy" of the triple concentrated pastes were evaluated by three supervised pattern recognition procedures, linear discriminant analysis (LDA), soft independent modeling of class analogy (SIMCA) and K-nearest neighbors (KNN).
Abstract: The concentration of 32 elements (Al, As, Ba, Be, Ca, Cd, Ce, Cu, Dy, Fe, K, La, Lu, Mg, Mn, Na, Nd, Pb, Rb, Sm, Sr, Th, U, V, Zn) was determined in tomatoes harvested in different four Italian regions and in triple concentrated tomato paste samples coming from Italy, China, Greece and California. The resulting multielement profiles were processed using three chemometric techniques to evaluate the possibility of discrimination between different cultivation areas. The closed-vessel microwave digested samples were diluted and analyzed by DRC-ICP-MS with CH4 as reaction gas. The accuracy of the proposed method was considered acceptable (values in the range 75−120%) for 25 out of the 35 elements of the reference material NCS ZC85006 Tomato. The origin of tomato fruits and the areas of production as “Italy” and “non-Italy” of the triple concentrated pastes were evaluated by three supervised pattern recognition procedures, linear discriminant analysis (LDA), soft independent modeling of class analogy (SIMCA) an...

65 citations

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TL;DR: The developed protocol represents a simple, rapid and selective tool for assaying these acidic biomarkers in urine samples for neuroendocrine cancer diagnosis and provides satisfactory results.

65 citations

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TL;DR: A reliable classification of onion samples in groups corresponding to "Tropea" and "non-TropeA" categories is now available to the producers through the evaluation of three supervised chemometric approaches.
Abstract: Tropea red onion ( Allium cepa L. var. Tropea) is among the most highly appreciated Italian products. It is cultivated in specific areas of Calabria and, due to its characteristics, was recently awarded with the protected geographical indications (PGI) certification from the European Union. A reliable classification of onion samples in groups corresponding to "Tropea" and "non-Tropea" categories is now available to the producers. This important goal has been achieved through the evaluation of three supervised chemometric approaches. Onion samples with PGI brand (120) and onion samples not cultivated following the production regulations (80) were digested by a closed-vessel microwave oven system. ICP-MS equipped with a dynamic reaction cell was used to determine the concentrations of 25 elements (Al, Ba, Ca, Cd, Ce, Cr, Dy, Eu, Fe, Ga, Gd, Ho, La, Mg, Mn, Na, Nd, Ni, Pr, Rb, Sm, Sr, Tl, Y, and Zn). The multielement fingerprint was processed using linear discriminant analysis (LDA) (standard and stepwise), soft independent modeling of class analogy (SIMCA), and back-propagation artificial neural network (BP-ANN). The cross-validation procedure has shown good results in terms of the prediction ability for all of the chemometric models: standard LDA, 94.0%; stepwise LDA, 94.5%; SIMCA, 95.5%; and BP-ANN, 91.5%.

65 citations

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TL;DR: Tests showed that the proposed method did not significantly influenced by matrix effects in most of the cases tested, and thus allows the use of simplified calibration procedure, and satisfactory values of accuracy and precision were also obtained for all the matrices considered.

61 citations


Cited by
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TL;DR: In this paper, a unifying stratigraphic framework of the Messinian Salinity Crisis (MSC) events has been constructed, derived mainly from onshore data and observations, but incorporating different perspectives for the offshore and provides hypotheses that can be tested by drilling the deep Mediterranean basins.

449 citations

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339 citations

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TL;DR: The aim of the present work is to provide an overview of the different MS-based strategies that have been (or can be) applied in the new field of Foodomics, discussing their advantages and drawbacks.
Abstract: Modern research in food science and nutrition is moving from classical methodologies to advanced analytical strategies in which MS-based techniques play a crucial role. In this context, Foodomics has been recently defined as a new discipline that studies food and nutrition domains through the application of advanced omics technologies in which MS techniques are considered indispensable. Applications of Foodomics include the genomic, transcriptomic, proteomic, and/or metabolomic study of foods for compound profiling, authenticity, and/or biomarker-detection related to food quality or safety; the development of new transgenic foods, food contaminants, and whole toxicity studies; new investigations on food bioactivity, food effects on human health, etc. This review work does not intend to provide an exhaustive revision of the many works published so far on food analysis using MS techniques. The aim of the present work is to provide an overview of the different MS-based strategies that have been (or can be) applied in the new field of Foodomics, discussing their advantages and drawbacks. Besides, some ideas about the foreseen development and applications of MS-techniques in this new discipline are also provided.

335 citations

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TL;DR: The ability to tolerate large tissue Se concentrations is primarily related to the ability to divert Se away from the accumulation of selenocysteine and selenomethionine, which might be incorporated into non-functional proteins, through the synthesis of less toxic Se metabilites.

292 citations

Journal ArticleDOI
TL;DR: The purpose of this review is to summarise and describe the recent metabolomic applications in the area of food authentication and to discuss its current limitations and future potential.

258 citations