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Audrey E. Brynes
Researcher at Imperial College London
Publications - 42
Citations - 10274
Audrey E. Brynes is an academic researcher from Imperial College London. The author has contributed to research in topics: Insulin & Postprandial. The author has an hindex of 29, co-authored 42 publications receiving 9919 citations. Previous affiliations of Audrey E. Brynes include Hammersmith Hospital.
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Journal ArticleDOI
Ghrelin enhances appetite and increases food intake in humans.
Alison M. Wren,L. J. Seal,Mark Cohen,Audrey E. Brynes,Gary Frost,Kevin Murphy,Waljit S. Dhillo,M. A. Ghatei,S.R. Bloom +8 more
TL;DR: Ghrelin is the first circulating hormone demonstrated to stimulate food intake in man and is a potentially important new regulator of the complex systems controlling food intake and body weight.
Journal ArticleDOI
Gut hormone PYY 3-36 physiologically inhibits food intake
Rachel L. Batterham,Michael A. Cowley,Caroline J. Small,Herbert Herzog,Mark Cohen,C. L. Dakin,Alison M. Wren,Audrey E. Brynes,Malcolm J. Low,Mohammad A. Ghatei,Roger D. Cone,Stephen R. Bloom +11 more
TL;DR: In this paper, the authors showed that post-prandial elevation of PYY3-36 may act through the arcuate nucleus Y2R to inhibit feeding in a gut-hypothalamic pathway.
Journal Article
BRIEF COMMUNICATION ARISING: Gut hormone PYY3-36 physiologically inhibits food intake
Rachel L. Batterham,Michael A. Cowley,Caroline J. Small,Herbert Herzog,Mark A Cohen,C. L. Dakin,Alison M. Wren,Audrey E. Brynes,Malcolm J. Low +8 more
TL;DR: The authors showed that post-prandial elevation of PYY3-36 may act through the arcuate nucleus Y2R to inhibit feeding in a gut-hypothalamic pathway.
Journal ArticleDOI
Human gene for physical performance
Hugh Montgomery,Richard P. Marshall,Harry Hemingway,Saul G. Myerson,P. Clarkson,C T Dollery,Martin Hayward,D. E. Holliman,Mick Jubb,E L Thomas,Audrey E. Brynes,N. Saeed,Maria Barnard,Jimmy D. Bell,K Prasad,Mark P. Rayson,P.J. Talmud,S.E. Humphries +17 more
TL;DR: It is shown that a polymorphism in the gene encoding angiotensin-converting enzyme is associated with elite endurance performance among high-altitude mountaineers and after physical training, repetitive weight-lifting is improved eleven-fold in individuals homozygous for the ‘insertion’ allele.
Journal ArticleDOI
Exendin-4 reduces fasting and postprandial glucose and decreases energy intake in healthy volunteers
C. Mark B. Edwards,Sarah Stanley,Rachel Davis,Audrey E. Brynes,Gary Frost,L. J. Seal,Mohammad A. Ghatei,Stephen R. Bloom +7 more
TL;DR: The results are in accord with the possibility that exendin-4 may be a potential treatment for type 2 diabetes, particularly for obese patients, because it acts to reduce plasma glucose at least partly by a delay in gastric emptying, as well as by reducing calorie intake.