Author
Avijit Banerji
Bio: Avijit Banerji is an academic researcher from University of Calcutta. The author has contributed to research in topics: Cycloaddition & Aryl. The author has an hindex of 16, co-authored 121 publications receiving 911 citations.
Topics: Cycloaddition, Aryl, 1,3-Dipolar cycloaddition, Nitrone, Carbon-13 NMR
Papers published on a yearly basis
Papers
More filters
17 citations
TL;DR: In this article, a DFT/B3LYP/6-31G* study was carried out to predict the regio-and stereoselectivities of 1,3-dipolar cycloadditions of C,N-disubstituted aldonitrones to chalcones in terms of FMO theory, DFT-based reactivity indices, and activation energy calculations.
Abstract: A DFT/B3LYP/6-31G* study was carried out to predict the regio- and stereoselectivities of 1,3-dipolar cycloadditions of C,N-disubstituted aldonitrones to chalcones in terms of FMO theory, DFT-based reactivity indices, and activation energy calculations. The structures of the resultant 2,3,4,5-tetrasubstituted isoxazolidines were determined by means of NMR spectroscopy and X-ray analysis.
16 citations
16 citations
TL;DR: The structure of N-isobutyl-4,5-dihydroxy-2(E)-decenamide for sylvamide is confirmed by its total synthesis as mentioned in this paper.
16 citations
TL;DR: Karanjapin and karanjachromene were found to possess significant antioxidant activity and may play an important role in the pathogenesis of several diseases.
Abstract: The root bark of Pongamia pinnata Pierre [syn P. glabra (family: Fabaceae)] afforded a new chalcone (karanjapin) and two known flavonoids, a pyranoflavonoid (karanjachromene) and a furanoflavonoid (karanjin) The structure of karanjapin has been established from extensive 2D NMR spectral studies as beta,2'-dihydroxy-a,4'-dimethoxy-3,4-methylenedioxychalcone. Karanjapin and karanjachromene were found to possess significant antioxidant activity. This may play an important role in the pathogenesis of several diseases.
15 citations
Cited by
More filters
TL;DR: This tutorial review describes selected recent examples of how the metal-catalysed C-H bond functionalisation has been able to positively affect the synthesis of natural products.
Abstract: Metal-catalysed C–H bond functionalisation has had a significant impact on how chemists make molecules. Translating the methodological developments to their use in the assembly of complex natural products is an important challenge for the continued advancement of chemical synthesis. In this tutorial review, we describe selected recent examples of how the metal-catalysed C–H bond functionalisation has been able to positively affect the synthesis of natural products.
1,361 citations
947 citations
TL;DR: The secondary metabolites isolated from Piper species for the period 1907 to June 1996 have been reviewed in this paper, where nearly six hundred chemical constituents belonging to different classes of bioactive compounds are listed together with their source(s) and references.
849 citations
TL;DR: This review describes the biochemistry of tubulin, microtubules, and the mitotic spindle and describes the natural and synthetic agents which are known to interact with tubulin.
Abstract: Tubulin is the biochemical target for several clinically used anticancer drugs, including paclitaxel and the vinca alkaloids vincristine and vinblastine. This review describes both the natural and synthetic agents which are known to interact with tubulin. Syntheses of the more complex agents are referenced and the potential clinical use of the compounds is discussed. This review describes the biochemistry of tubulin, microtubules, and the mitotic spindle. The agents are discussed in relation to the type of binding site on the protein with which they interact. These are the colchicine, vinca alkaloid, rhizoxin/maytansine, and tubulin sulfhydryl binding sites. Also included are the agents which either bind at other sites or unknown sites on tubulin. The literature is reviewed up to October 1997. © 1998 John Wiley & Sons, Inc., Med Res Rev, 18, No. 4, 259–296, 1998.
624 citations
TL;DR: Recently completed total syntheses showcasing creative and ingenious incorporation of C-Hactivation as a strategic manoeuver are compared with their "non-C-H activation" counterparts, illuminating a new paradigm in strategic synthetic design.
Abstract: The recent advent of transition-metal mediated CH activation is revolutionizing the synthetic field and gradually infusing a “CH activation mind-set” in both students and practitioners of organic synthesis. As a powerful testament of this emerging synthetic tool, applications of CH activation in the context of total synthesis of complex natural products are beginning to blossom. Herein, recently completed total syntheses showcasing creative and ingenious incorporation of CH activation as a strategic manoeuver are compared with their “non-CH activation” counterparts, illuminating a new paradigm in strategic synthetic design.
439 citations