A
Axel Kallies
Researcher at University of Melbourne
Publications - 195
Citations - 18665
Axel Kallies is an academic researcher from University of Melbourne. The author has contributed to research in topics: Cellular differentiation & Cytotoxic T cell. The author has an hindex of 61, co-authored 179 publications receiving 15018 citations. Previous affiliations of Axel Kallies include Free University of Berlin & Walter and Eliza Hall Institute of Medical Research.
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Journal ArticleDOI
Foxp3+ follicular regulatory T cells control the germinal center response
Michelle A. Linterman,Wim Pierson,Sau K. Lee,Axel Kallies,Shimpei Kawamoto,Tim F. Rayner,Monika Srivastava,Devina Divekar,Laura L. Beaton,Jennifer J. Hogan,Sidonia Fagarasan,Adrian Liston,Kenneth G. C. Smith,Carola G. Vinuesa +13 more
TL;DR: A population of Foxp3+Blimp-1+CD4+ T cells constituting 10–25% of the CXCR5highPD-1highCD4- T cells found in the germinal center after immunization with protein antigens are described.
Journal ArticleDOI
Defining ‘T cell exhaustion’
Christian U. Blank,W. Nicholas Haining,Werner Held,Patrick G. Hogan,Patrick G. Hogan,Axel Kallies,Enrico Lugli,Rachel C. Lynn,Mary Philip,Anjana Rao,Anjana Rao,Nicholas P. Restifo,Andrea Schietinger,Ton N. Schumacher,Pamela L. Schwartzberg,Arlene H. Sharpe,Daniel E. Speiser,E. John Wherry,Benjamin Youngblood,Dietmar Zehn +19 more
TL;DR: In this Viewpoint article, 18 experts in the field tell us what exhaustion means to them, ranging from complete lack of effector function to altered functionality to prevent immunopathology, with potential differences between cancer and chronic infection.
Journal ArticleDOI
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism.
Dimitra Zotos,Jonathan M. Coquet,Yang Zhang,Amanda Light,Kathy D'Costa,Axel Kallies,Lynn M. Corcoran,Dale I. Godfrey,Kai-Michael Toellner,Mark J. Smyth,Stephen L. Nutt,David M. Tarlinton +11 more
TL;DR: It is shown that the absence of IL-21 signaling profoundly affects the B cell response to protein antigen, reducing splenic and bone marrow plasma cell formation and GC persistence and function, influencing their proliferation, transition into memory B cells, and affinity maturation.
Journal ArticleDOI
Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.
Laura K. Mackay,Laura K. Mackay,Martina Minnich,Natasja A. M. Kragten,Yang Liao,Yang Liao,Benjamin Nota,Cyril Seillet,Cyril Seillet,Ali Zaid,Kevin Man,Kevin Man,Simon Preston,Simon Preston,David Freestone,Asolina Braun,Erica Wynne-Jones,Felix M. Behr,Regina Stark,Daniel G. Pellicci,Daniel G. Pellicci,Dale I. Godfrey,Dale I. Godfrey,Gabrielle T. Belz,Gabrielle T. Belz,Marc Pellegrini,Marc Pellegrini,Thomas Gebhardt,Meinrad Busslinger,Wei Shi,Wei Shi,Francis R. Carbone,René A. W. van Lier,Axel Kallies,Axel Kallies,Klaas P. J. M. van Gisbergen +35 more
TL;DR: In this paper, the authors identify Hobit and Blimp1 as central regulators of a universal program that instructs tissue retention in diverse tissue-resident lymphocyte populations, including NKT cells and liver-resident NK cells.
Journal Article
Animal biodiversity: An outline of higher-level classification and survey of taxonomic richness
Zhi-Qiang Zhang,John Na Hooper,Rob W. M. Van Soest,Andrzej Pisera,Andrea L. Crowther,Seth Tyler,Stephen Schilling,William N. Eschmeyer,Jon D. Fong,David C. Blackburn,David B. Wake,Don E. Wilson,DeeAnn M. Reeder,Uwe Fritz,Mike Hodda,Roberto Guidetti,Roberto Bertolani,Georg Mayer,Ivo de Sena Oliveira,Jonathan M. Adrain,Roger N. Bamber,Adriano B. Kury,Lorenzo Prendini,Mark S. Harvey,Frédéric Beaulieu,Ashley P. G. Dowling,Hans Klompen,Gilberto J. de Moraes,David Evans Walter,Qing-Hai Fan,Vladimir Pešić,Harry Smit,Andre V. Bochkov,AA Khaustov,Anne S. Baker,Andreas Wohltmann,Tinghuan Wen,James W. Amrine,P Beron,Jianzhen Lin,Grzegorz Gabrys,Robert W. Husband,Samuel J. Bolton,M Uusitalo,Heinrich Schatz,Valerie M. Behan-Pelletier,Barry M. OConnor,Roy A. Norton,Jason A. Dunlop,David Penney,Alessandro Minelli,William A. Shear,Shane T. Ahyong,James K. Lowry,Miguel Alonso,Geoffrey A. Boxshall,Peter Castro,Sarah Gerken,Gordan S. Karaman,Joseph W. Goy,Diana S. Jones,Kenneth Meland,D. Christopher Rogers,Jrundur Svavarsson,Frans Janssens,Kenneth Christiansen,Sigfrid Ingrisch,Paul D. Brock,Judith Marshall,George W. Beccaloni,Paul Eggleton,Laurence A. Mound,S. A. Slipinski,Rab Leschen,John F. Lawrence,Ralph W. Holzenthal,John C. Morse,Karl M. Kjer,Erik J. van Nieukerken,Lauri Kaila,Ian J. Kitching,Niels P. Kristensen,David C. Lees,Joël Minet,Charles Mitter,Marko Mutanen,Jerome C. Regier,Thomas J. Simonsen,Niklas Wahlberg,Shen-Horn Yen,Reza Zahiri,David Adamski,Joaquin Baixeras,Daniel Bartsch,Bengt Å. Bengtsson,John W. Brown,Sibyl R. Bucheli,Donald R. Davis,Jurate De Prins,Willy De Prins,Marc E. Epstein,Patricia Gentili-Poole,Cees Gielis,Peter Haettenschwiler,Axel Hausmann,Jeremy D. Holloway,Axel Kallies,Ole Karsholt,Akito Y. Kawahara,Sjaak J C Koster,Mikhail V. Kozlov,J. Donald Lafontaine,Gerardo Lamas,Jean-François Landry,Sangmi Lee,Matthias Nuss,Kyu-Tek Park,Carla M. Penz,Jadranka Rota,Alexander Schintlmeister,B. Christian Schmidt,Jae-Cheon Sohn,M. Alma Solis,Gerhard M. Tarmann,Andrew D. Warren,Susan J. Weller,Roman V. Yakovlev,Vadim V. Zolotuhin,Andreas Zwick,Thomas Pape,Vladimir Blagoderov,Mikhail B. Mostovski,Christian C. Emig,Hendrik Segers,Scott Monks,Dennis J. Richardson +135 more